Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.39 |
| ▸ | KLK1 | P06870 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 3/20 | 0.35 |
| ▸ | MC5R | P33032 | 1/20 | 0.35 |
| ▸ | MC3R | P41968 | 1/20 | 0.35 |
| ▸ | MC1R | Q01726 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4255915 | 0.93 | KIF11 (0.40) | ALDH1A1KIF11 | |
| SCHEMBL4245630 | 0.93 | KIF11 (0.41) | ALDH1A1KIF11 | |
| SCHEMBL4252370 | 0.91 | KIF11 (0.37) | ALDH1A1KIF11MEN1KMT2A | |
| SCHEMBL4245138 | 0.91 | KIF11 (0.45) | ALDH1A1KIF11KMT2AMC4R | |
| SCHEMBL4255895 | 0.89 | KIF11 (0.36) | ALDH1A1KIF11LMNAGAA | |
| SCHEMBL4251314 | 0.88 | KIF11 (0.36) | ALDH1A1KIF11LPAR1 | |
| SCHEMBL4249156 | 0.88 | KIF11 (0.40) | KIF11 | |
| SCHEMBL4255871 | 0.80 | KIF11 (0.43) | PDE1BKIF11 | |
| SCHEMBL4255872 | 0.79 | PDE1B (0.38) | PDE1BKLK1ALDH1A1KIF11MEN1 | |
| SCHEMBL4250107 | 0.79 | KIF11 (0.51) | KIF11HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035426-A1 | PYRAZOLOPYRIMIDONES | 4SC AG (DE) | 2009-03-18 | — | — | EP | disclosed |
| WO-2007144384-A1 | PYRAZOLOPYRIMIDONES | 4SC AG (DE) | 2007-12-21 | — | — | WO | disclosed |