SCHEMBL4256417

SCHEMBL4256417

C=CC(O)c1ccc(S(N)(=O)=O)cc1

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA2 P00918 18/20 0.50
CA9 Q16790 16/20 0.50
CA1 P00915 15/20 0.50
CA12 O43570 13/20 0.50
CA14 Q9ULX7 7/20 0.50
ALDH1A1 P00352 1/20 0.46
CA7 P43166 7/20 0.44
CA5A P35218 6/20 0.44
CA5B Q9Y2D0 6/20 0.44
CA6 P23280 5/20 0.43
CA4 P22748 3/20 0.43
CA13 Q8N1Q1 2/20 0.43
USP2 O75604 1/20 0.43
TSHR P16473 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
AGO2 Q9UKV8 1/20 0.43
CA3 P07451 3/20 0.42
CYP2C19 P33261 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11869672 0.78 ALDH1A1 (0.47) CA2CA9CA1CA12CA14
SCHEMBL398361 0.76 CA2 (0.46) CA2CA9CA1CA12CA14
SCHEMBL28575526 0.74 ALDH1A1 (0.60) CA2CA9CA1CA12CA14
SCHEMBL21733100 0.73 CA2 (0.53) CA2CA9CA1CA12CA14
SCHEMBL393905 0.73 TDP1 (0.61) CA2CA9CA1CA12CA14
SCHEMBL6404428 0.73 MAPT (0.38) CA14ALDH1A1CA6TSHRTDP1
SCHEMBL28246182 0.72 CA2 (0.51) CA2CA9CA1CA12CA14
SCHEMBL9492465 0.71 TDP1 (0.59) CA2CA9CA1CA12CA14
Lithium SCHEMBL31621904 0.71 TDP1 (0.59) CA2CA9CA1CA12CA14
Ammonia Solution, Strong SCHEMBL28392198 0.71 TDP1 (0.59) CA2CA9CA1CA12CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2105298-A1 Negative-working lithographic printing plate precursor and method of lithographic printing using same Fujifilm Corporation (JP) 2009-09-30 EP disclosed