⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1489852 | 0.91 | DRD2 (0.34) | — | |
| SCHEMBL7047862 | 0.85 | DRD2 (0.38) | — | |
| SCHEMBL42184 | 0.84 | GNAI3 (0.43) | — | |
| SCHEMBL651943 | 0.82 | GNAO1 (0.52) | — | |
| SCHEMBL10593959 | 0.80 | GNAO1 (0.55) | — | |
| SCHEMBL10776413 | 0.80 | GNAO1 (0.55) | — | |
| SCHEMBL4681475 | 0.80 | GNAO1 (0.55) | — | |
| SCHEMBL10773791 | 0.80 | GNAO1 (0.55) | — | |
| SCHEMBL9433020 | 0.80 | GNAO1 (0.55) | — | |
| SCHEMBL9432137 | 0.80 | GNAO1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 547 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115108931-B | Tofenamic acid derivative and preparation and application thereof | 南华大学附属第一医院 | 2024-06-14 | — | — | CN | claimed |
| US-20240115553-A1 | COMPOSITIONS AND METHODS FOR TREATING BRAIN INJURY | AZEVAN PHARMACEUTICALS, INC. (US) | 2024-04-11 | — | — | US | claimed |
| CN-115108931-A | Tofenamic acid derivative and preparation and application thereof | 南华大学附属第一医院 | 2022-09-27 | — | — | CN | claimed |
| US-11319306-B2 | Compositions and methods for treating neurodegenerative diseases | AZEVAN PHARMACEUTICALS, INC. (US) | 2022-05-03 | — | — | US | claimed |
| CN-114127065-A | Compounds for the treatment of neurodegenerative diseases and cancer | 鸿仪有限责任公司 | 2022-03-01 | — | — | CN | claimed |
| US-20220048893-A1 | Compounds for Treating Neurodegenerative Diseases and Cancers | HONGYI & ASS LLC (US) | 2022-02-17 | — | — | US | claimed |
| EP-3935057-A1 | COMPOUNDS FOR TREATING NEURODEGENERATIVE DISEASES AND CANCERS | Hongyi & Associates LLC (US) | 2022-01-12 | — | — | EP | claimed |
| CN-108864007-B | 2-aminomethyl-6- (benzofuran-5-yl) phenol and preparation method and application thereof | 湖南大学 | 2020-08-04 | — | — | CN | claimed |
| EP-2544535-B1 | PHENOXY THIOPHENE SULFONAMIDES AND THEIR USE AS INHIBITORS OF GLUCURONIDASE | NORTH CAROLINA CENTRAL UNIV (US) | 2017-04-19 | — | — | EP | claimed |
| EP-2314586-B1 | 2-Acylaminothiazole derivative or salt thereof | ASTELLAS PHARMA INC (JP) | 2016-09-14 | — | — | EP | claimed |
| EP-0606658-B1 | Substituted N-aminoalkylmethansulphoamides as antispasmodic agents | ROEMMERS SA (AR) | 1996-05-01 | — | — | EP | claimed |
| EP-0290145-B1 | Aliphatic carboxamides | ICI AMERICA INC (US) | 1994-10-26 | — | — | EP | claimed |
| EP-0606658-A1 | Substituted N-aminoalkylmethansulphoamides as antispasmodic agents | ROEMMERS S.A.I.C.F. (AR) | 1994-07-20 | — | — | EP | claimed |
| US-4958024-A | REACTION OF CARBAMATE SUBSTITUTED ACRYLIC ESTER, VASODILATORS, HYPOTENSIVE AGENTS | BANYU PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-09-18 | — | — | US | claimed |
| US-4914227-A | FOR VASODILATING AND HYPOTENSIVE AGENTS | BANYU PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-04-03 | — | — | US | claimed |
| US-4739106-A | VASODILATION, HYPOTENSIVE AGENTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1988-04-19 | — | — | US | claimed |
| EP-0101023-B1 | PROCESS FOR PREPARING 2-CARBAMOYLOXYALKYL-1,4-DIHYDROPYRIDINE DERIVATIVES AND INTERMEDIATES USEFUL FOR THE PROCESS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1987-07-29 | — | — | EP | claimed |
| US-4599419-A | ANTICOAGULANTS | MITSUBISHI CHEMICAL INDUSTRIES, INC. (JP) | 1986-07-08 | — | — | US | claimed |
| EP-0101023-A1 | Process for preparing 2-carbamoyloxyalkyl-1,4-dihydropyridine derivatives and intermediates useful for the process | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1984-02-22 | — | — | EP | claimed |
| US-4108994-A | 5-THIAZOLE-METHANE-AMINES, AND THEIR USE AS ANTILIPOLYTICS | ROUSSEL UCLAF (FR) | 1978-08-22 | — | — | US | claimed |