Serotonin

Serotonin

SCHEMBL4257033

NCCc1c[nH]c2ccc(O)cc12.ONCCc1c[nH]c2ccccc12

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 6/20 0.71
CYP2D6 P10635 4/20 0.71
HTR2A P28223 3/20 0.71
HTR1A P08908 3/20 0.71
CYP1A2 P05177 3/20 0.71
CYP3A4 P08684 3/20 0.71
HTR1D P28221 3/20 0.71
HTR1B P28222 3/20 0.71
HTR2B P41595 2/20 0.71
HTR7 P34969 2/20 0.71
HTR6 P50406 2/20 0.71
TAAR1 Q96RJ0 2/20 0.71
HTR3E A5X5Y0 1/20 0.71
HTR3B O95264 1/20 0.71
CYP2C9 P11712 1/20 0.71
TSHR P16473 1/20 0.71
DRD1 P21728 1/20 0.71
HTR1E P28566 1/20 0.71
HTR1F P30939 1/20 0.71
DRD3 P35462 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Serotonin SCHEMBL798285 0.91 HTR2A (0.85) HTR2CCYP2D6HTR2AHTR1ACYP1A2
SCHEMBL27788551 0.87 HTR2C (0.75) HTR2CCYP2D6HTR2AHTR1ACYP1A2
Serotonin SCHEMBL1495 0.84 HTR2C (1.00) HTR2CCYP2D6HTR2AHTR1ACYP1A2
Serotonin SCHEMBL29349412 0.84 HTR2C (1.00) HTR2CCYP2D6HTR2AHTR1ACYP1A2
Serotonin SCHEMBL183226 0.84 HTR2C (1.00) HTR2CCYP2D6HTR2AHTR1ACYP1A2
Serotonin SCHEMBL30057954 0.84 HTR2C (1.00) HTR2CCYP2D6HTR2AHTR1ACYP1A2
Serotonin SCHEMBL25341783 0.83 HTR2C (1.00) HTR2CCYP2D6HTR2AHTR1ACYP1A2
Serotonin SCHEMBL396997 0.83 HTR2C (0.97) HTR2CCYP2D6HTR2AHTR1ACYP1A2
Serotonin SCHEMBL29781387 0.83 HTR2C (1.00) HTR2CCYP2D6HTR2AHTR1ACYP1A2
Serotonin SCHEMBL1675866 0.83 HTR2C (0.97) HTR2CCYP2D6HTR2AHTR1ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090054414-A1 Rufinamide for the Treatment of Post-Traumatic Stress Disorder SYNOSIA THERAPEUTICS (US) 2009-02-26 US claimed
CN-109387625-A For diagnosing the binding analysis method of heparin-induced property thrombopenia 西门子医学诊断产品有限责任公司 2019-02-26 CN disclosed
CN-108490204-A System and method for multiple analysis 赛拉诺斯知识产权有限责任公司 2018-09-04 CN disclosed
CN-103946364-B system and method for multiplex analysis 赛拉诺斯知识产权有限责任公司 2018-04-24 CN disclosed
CN-104694628-B Using the activated polymerization nucleic acid reacted by polyphosphoric acid decomposition (APP) 生命技术公司 2017-06-06 CN disclosed
US-20150126819-A1 NEUROLOGICAL STIMULUS FOR THE PREVENTION OF SUDDEN INFANT DEATH SYNDROME (SIDS) ELEMENT 1 SYSTEMS LLC 2015-05-07 US disclosed
US-8942783-B2 Stochastic resonance and brownian motion for the reduction of sudden infant death syndrome (SIDS) ELEMENT 1 SYSTEMS LLC (US) 2015-01-27 US disclosed
US-20130144152-A1 STOCHASTIC RESONANCE AND BROWNIAN MOTION FOR THE REDUCTION OF SUDDEN INFANT DEATH SYNDROME (SIDS) ELEMENT 1 SYSTEMS LLC (US) 2013-06-06 US disclosed
CN-101802609-A peptide probes for diagnostics and therapeutics ADLYFE INC 2010-08-11 CN disclosed
US-20090054414-A1 Rufinamide for the Treatment of Post-Traumatic Stress Disorder SYNOSIA THERAPEUTICS (US) 2009-02-26 US disclosed
US-5128326-A Drug delivery systems based on hyaluronans derivatives thereof and their salts and methods of producing same BIOMATRIX, INC. (US) 1992-07-07 US disclosed
EP-0224987-B1 DRUG DELIVERY SYSTEMS BASED ON HYALURONAN, DERIVATIVES THEREOF AND THEIR SALTS AND METHOD OF PRODUCING SAME Biomatrix, Inc. (US) 1992-04-15 EP disclosed
EP-0224987-A2 Drug delivery systems based on hyaluronan, derivatives thereof and their salts and method of producing same Biomatrix, Inc. (US) 1987-06-10 EP disclosed