Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.58 |
| ▸ | MGLL | Q99685 | 4/20 | 0.55 |
| ▸ | FAAH | O00519 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | F12 | P00748 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 7/20 | 0.43 |
| ▸ | MGAM | O43451 | 6/20 | 0.43 |
| ▸ | AMY1A | P0DUB6 | 6/20 | 0.43 |
| ▸ | SI | P14410 | 6/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 6/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL425437 | 0.85 | GAA (0.52) | MGLLFAAHKMT2AMAPTNPSR1 | |
| SCHEMBL425705 | 0.83 | MGAM (0.56) | MGLLFAAHKMT2AMAPTNPSR1 | |
| SCHEMBL426868 | 0.83 | F12 (0.53) | MGLLFAAHKMT2AMAPTNPSR1 | |
| SCHEMBL426870 | 0.82 | FAAH (0.56) | MGLLFAAHKMT2AMAPTNPSR1 | |
| SCHEMBL426780 | 0.75 | ASAH1 (0.54) | TRPV1MGLLFAAHKMT2AMAPT | |
| SCHEMBL425007 | 0.74 | KMT2A (0.61) | KMT2AMAPTNPSR1KDM4EALDH1A1 | |
| SCHEMBL26027596 | 0.74 | TRPV1 (0.51) | TRPV1MGLLKMT2AHPGD | |
| SCHEMBL426724 | 0.74 | ASAH1 (0.56) | FAAHKMT2AMAPTNPSR1KDM4E | |
| SCHEMBL426846 | 0.73 | ASAH1 (0.58) | TRPV1MGLLFAAHKMT2AMAPT | |
| SCHEMBL11882946 | 0.72 | ASAH1 (0.60) | FAAHKMT2AMAPTNPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9353082-B2 | Pharmaceutical compounds | BIAL—PORTELA & CA, S.A. (PT) | 2016-05-31 | — | — | US | disclosed |
| US-9353082-B2 | Pharmaceutical compounds | BIAL—PORTELA & CA, S.A. (PT) | 2016-05-31 | — | — | US | disclosed |
| US-20120065191-A1 | PHARMACEUTICAL COMPOUNDS | BIAL - PORTELA & Cª, S.A. (PT) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065191-A1 | PHARMACEUTICAL COMPOUNDS | FAAH, FAAH2, ASAH1 | TRPV1 165/4885MGLL 11/4885FAAH 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.