Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 10/20 | 0.58 |
| ▸ | MGAM | O43451 | 9/20 | 0.58 |
| ▸ | AMY1A | P0DUB6 | 9/20 | 0.58 |
| ▸ | SI | P14410 | 9/20 | 0.58 |
| ▸ | MGAM2 | Q2M2H8 | 9/20 | 0.58 |
| ▸ | F2 | P00734 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.58 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.56 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.54 |
| ▸ | F12 | P00748 | 6/20 | 0.53 |
| ▸ | MIF | P14174 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL425777 | 0.84 | KMT2A (0.56) | KMT2AMAPTALDH1A1NPSR1KDM4E | |
| SCHEMBL425552 | 0.84 | KMT2A (0.59) | KMT2AMAPTALDH1A1NPSR1KDM4E | |
| SCHEMBL427308 | 0.83 | KMT2A (0.70) | KMT2AMAPTALDH1A1NPSR1KDM4E | |
| SCHEMBL425437 | 0.81 | GAA (0.52) | KMT2AMAPTALDH1A1NPSR1KDM4E | |
| SCHEMBL445704 | 0.81 | GAA (0.52) | KMT2AMAPTALDH1A1NPSR1KDM4E | |
| SCHEMBL7899312 | 0.81 | KMT2A (0.59) | KMT2AMAPTALDH1A1NPSR1KDM4E | |
| SCHEMBL427748 | 0.81 | GAA (0.52) | KMT2AMAPTALDH1A1NPSR1KDM4E | |
| SCHEMBL535054 | 0.80 | GAA (0.64) | KMT2AMAPTALDH1A1NPSR1KDM4E | |
| SCHEMBL706083 | 0.80 | MGAM (0.68) | KMT2AMAPTALDH1A1NPSR1KDM4E | |
| SCHEMBL4250719 | 0.80 | GAA (0.68) | KMT2AMAPTALDH1A1NPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2566335-B1 | CONTROLLED RELEASE OF ACTIVE COMPOUNDS FROM MACROMOLECULAR CONJUGATES | PROLYNX LLC (US) | 2016-06-29 | — | — | EP | disclosed |
| US-9353082-B2 | Pharmaceutical compounds | BIAL—PORTELA & CA, S.A. (PT) | 2016-05-31 | — | — | US | disclosed |
| US-9353082-B2 | Pharmaceutical compounds | BIAL—PORTELA & CA, S.A. (PT) | 2016-05-31 | — | — | US | disclosed |
| US-9353082-B2 | Pharmaceutical compounds | BIAL—PORTELA & CA, S.A. (PT) | 2016-05-31 | — | — | US | disclosed |
| US-20160139162-A1 | Inhibitors Of Fatty Acid Amide Hydrolase And Monoacylglycerol Lipase For Modulation Of Cannabinoid Receptors | NORTHEASTERN UNIVERSITY | 2016-05-19 | — | — | US | disclosed |
| US-20160139162-A1 | Inhibitors Of Fatty Acid Amide Hydrolase And Monoacylglycerol Lipase For Modulation Of Cannabinoid Receptors | NORTHEASTERN UNIVERSITY | 2016-05-19 | — | — | US | disclosed |
| US-20160139162-A1 | Inhibitors Of Fatty Acid Amide Hydrolase And Monoacylglycerol Lipase For Modulation Of Cannabinoid Receptors | NORTHEASTERN UNIVERSITY | 2016-05-19 | — | — | US | disclosed |
| US-9271962-B2 | Inhibitors of fatty acid amide hydrolase and monoacylglycerol lipase for modulation of cannabinoid receptors | NORTHEASTERN UNIVERSITY (US) | 2016-03-01 | — | — | US | disclosed |
| US-9271962-B2 | Inhibitors of fatty acid amide hydrolase and monoacylglycerol lipase for modulation of cannabinoid receptors | NORTHEASTERN UNIVERSITY (US) | 2016-03-01 | — | — | US | disclosed |
| US-9271962-B2 | Inhibitors of fatty acid amide hydrolase and monoacylglycerol lipase for modulation of cannabinoid receptors | NORTHEASTERN UNIVERSITY (US) | 2016-03-01 | — | — | US | disclosed |
| US-20130116407-A1 | CONTROLLED RELEASE FROM MACROMOLECULAR CONJUGATES | PROLYNX LLC | 2013-05-09 | — | — | US | disclosed |
| US-20120065191-A1 | PHARMACEUTICAL COMPOUNDS | BIAL - PORTELA & Cª, S.A. (PT) | 2012-03-15 | — | — | US | disclosed |
| US-20120065191-A1 | PHARMACEUTICAL COMPOUNDS | BIAL - PORTELA & Cª, S.A. (PT) | 2012-03-15 | — | — | US | disclosed |
| US-20120065191-A1 | PHARMACEUTICAL COMPOUNDS | BIAL - PORTELA & Cª, S.A. (PT) | 2012-03-15 | — | — | US | disclosed |
| WO-2011140376-A1 | CONTROLLED DRUG RELEASE FROM DENDRIMERS | PROLYNX LLC (US) | 2011-11-10 | — | — | WO | disclosed |
| US-20110166138-A1 | Inhibitors of Fatty Acid Amide Hydrolase and Monoacylglycerol Lipase for Modulation of Cannabinoid Receptors | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2011-07-07 | — | — | US | disclosed |
| US-20110166138-A1 | Inhibitors of Fatty Acid Amide Hydrolase and Monoacylglycerol Lipase for Modulation of Cannabinoid Receptors | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2011-07-07 | — | — | US | disclosed |
| US-20110166138-A1 | Inhibitors of Fatty Acid Amide Hydrolase and Monoacylglycerol Lipase for Modulation of Cannabinoid Receptors | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2011-07-07 | — | — | US | disclosed |
| WO-2009117444-A1 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE AND MONOACYLGLYCEROL LIPASE FOR MODULATION OF CANNABINOID RECEPTORS | NORTHEASTERN UNIVERSITY (US) | 2009-09-24 | — | — | WO | disclosed |
| US-4038403-A | INSECT AND ACARINA CONTROL | AMERICAN CYANAMID COMPANY (US) | 1977-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065191-A1 | PHARMACEUTICAL COMPOUNDS | FAAH, FAAH2, ASAH1 | KMT2A 2067/4885MAPT 1705/4885ALDH1A1 294/4885 |
| US-20130116407-A1 | CONTROLLED RELEASE FROM MACROMOLECULAR CONJUGATES | ABCB1, ABCB11, GUSB | KMT2A 3975/4885MAPT 728/4885ALDH1A1 1951/4885 |
| US-20110166138-A1 | Inhibitors of Fatty Acid Amide Hydrolase and Monoacylglycerol Lipase for Modulation of Cannabinoid Receptors | FAAH, FAAH2, MGLL | KMT2A 2131/4885MAPT 4313/4885ALDH1A1 1388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.