Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL75434 | 1.00 | ALDH1A1 (0.31) | ALDH1A1LMNA | |
| SCHEMBL4255753 | 0.88 | CNR2 (0.34) | ALDH1A1LMNA | |
| SCHEMBL4264917 | 0.87 | CNR2 (0.31) | ALDH1A1LMNA | |
| SCHEMBL75717 | 0.87 | HSD11B1 (0.34) | ALDH1A1LMNA | |
| SCHEMBL76306 | 0.87 | CNR2 (0.31) | ALDH1A1LMNA | |
| SCHEMBL4253450 | 0.87 | HSD11B1 (0.34) | ALDH1A1LMNA | |
| SCHEMBL1574084 | 0.83 | HSD11B1 (0.35) | — | |
| SCHEMBL4251570 | 0.83 | HSD11B1 (0.35) | — | |
| SCHEMBL75020 | 0.81 | HSD11B1 (0.31) | ALDH1A1 | |
| SCHEMBL4258518 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2104665-A2 | IMIDAZOLONE AND IMIDAZOLIDINONE DERIVATIVES AS 11B-HSD1 INHIBITORS FOR DIABETES | F. Hoffmann-Roche AG (CH) | 2009-09-30 | — | — | EP | claimed |
| WO-2008046758-A2 | IMIDAZOLONE AND IMIDAZOLIDINONE DERIVATIVES AS 11B-HSD1 INHIBITORS FOR DIABETES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-04-24 | — | — | WO | claimed |