SCHEMBL4258764

SCHEMBL4258764

C1=CC2CC1CC2C1CCc2ccccc21

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SRD5A1 P18405 3/20 0.40
CYP11B2 P19099 2/20 0.39
SIGMAR1 Q99720 5/20 0.38
IDO1 P14902 2/20 0.38
PDPK1 O15530 1/20 0.38
KDM1A O60341 1/20 0.37
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
AKR1C3 P42330 1/20 0.36
CYP17A1 P05093 1/20 0.36
CYP19A1 P11511 1/20 0.36
HTR1A P08908 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30177612 0.77 KDM1A (0.40) SIGMAR1KDM1A
SCHEMBL11671198 0.74 SRD5A1 (0.55) SRD5A1CYP11B2SIGMAR1IDO1PDPK1
Magnesium SCHEMBL31510119 0.72 SRD5A1 (0.53) SRD5A1CYP11B2SIGMAR1IDO1PDPK1
SCHEMBL5993533 0.71 CYP11B2 (0.54) CYP11B2IDO1PDPK1KDM1AMAOA
SCHEMBL8027234 0.71 SRD5A1 (0.38) SRD5A1CYP11B2SIGMAR1IDO1PDPK1
SCHEMBL4244043 0.68 MAOA (0.49) PDPK1KDM1AMAOAMAOB
SCHEMBL11983264 0.68 KDM4E (0.33) KDM1A
SCHEMBL6784204 0.67 IDO1 (0.53) SRD5A1SIGMAR1IDO1PDPK1
SCHEMBL2767254 0.67 SIGMAR1 (0.54) SRD5A1SIGMAR1IDO1PDPK1
SCHEMBL7932553 0.66 SIGMAR1 (0.53) SRD5A1SIGMAR1IDO1PDPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090292088-A1 PROCESS FOR PRODUCTION OF CYCLIC OLEFIN ADDITION POLYMER JSR CORPORATION (JP) 2009-11-26 US disclosed
US-7482412-B2 Process for manufacturing cycloolefin addition polymer JSR CORPORATION (JP) 2009-01-27 US disclosed
EP-1961774-A1 PROCESS FOR PRODUCTION OF CYCLIC OLEFIN ADDITION POLYMER JSR Corporation (JP) 2008-08-27 EP disclosed
US-20080085979-A1 PROCESS FOR MANUFACTURING CYCLOOLEFIN ADDITION POLYMER JSR CORPORATION (JP) 2008-04-10 US disclosed
US-7268196-B2 Process for producing cycloolefin addition polymer JSR CORPORATION (JP) 2007-09-11 US disclosed
US-7241847-B2 Process for producing cycloolefin addition polymer JSR CORPORATION (JP) 2007-07-10 US disclosed
US-20070155922-A1 Process for producing cycloolefin addition polymer JSR CORPORATION (JP) 2007-07-05 US disclosed
US-20070123667-A1 PROCESS FOR PRODUCING CYCLOOLEFIN ADDITION POLYMER JSR CORPORATION (JP) 2007-05-31 US disclosed
EP-1712572-A1 PROCESS FOR PRODUCING CYCLOOLEFIN ADDITION POLYMER JSR Corporation (JP) 2006-10-18 EP disclosed
US-20060217505-A1 Process for producing cycloolefin addition polymer JRS CORPORATION (JP) 2006-09-28 US disclosed
EP-1657259-A1 PROCESS FOR PRODUCING CYCLOOLEFIN ADDITION POLYMER JSR Corporation (JP) 2006-05-17 EP disclosed
US-7015293-B2 Cycloolefin addition copolymer and optical transparent material JSR CORPORATION (JP) 2006-03-21 US disclosed
US-20050171310-A1 Cycloolefin addition copolymer and optical transparent material JSR CORPORATION (JP) 2005-08-04 US disclosed
EP-1538169-A1 CYCLOOLEFIN ADDITION COPOLYMER AND OPTICAL TRANSPARENT MATERIAL JSR Corporation (JP) 2005-06-08 EP disclosed