Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4258814 | 1.00 | L3MBTL1 (0.33) | L3MBTL1MAOAABCB11CHRM2ACHE | |
| SCHEMBL4260486 | 0.71 | ABCB11 (0.33) | MAOAABCB11CHRM2ACHEPTGS1 | |
| SCHEMBL13351511 | 0.69 | CHRM2 (0.39) | MAOAABCB11CHRM2ACHEPTGS1 | |
| SCHEMBL4253287 | 0.67 | L3MBTL1 (0.38) | L3MBTL1CHRM2 | |
| SCHEMBL4253296 | 0.67 | L3MBTL1 (0.38) | L3MBTL1CHRM2 | |
| SCHEMBL4251597 | 0.67 | L3MBTL1 (0.34) | L3MBTL1 | |
| SCHEMBL4251587 | 0.67 | L3MBTL1 (0.34) | L3MBTL1 | |
| SCHEMBL13816974 | 0.66 | ADRA2A (0.33) | MAOANR1I2PGRADORA3PTGS2 | |
| SCHEMBL3499058 | 0.65 | — | — | |
| SCHEMBL4255879 | 0.64 | L3MBTL1 (0.36) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8268933-B2 | Polymers functionalized with polyimine compounds | BRIDGESTONE CORPORATION (JP) | 2012-09-18 | — | — | US | claimed |
| US-20090171035-A1 | POLYMERS FUNCTIONALIZED WITH POLYIMINE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2009-07-02 | — | — | US | claimed |
| US-8268933-B2 | Polymers functionalized with polyimine compounds | BRIDGESTONE CORPORATION (JP) | 2012-09-18 | — | — | US | disclosed |
| US-20090171035-A1 | POLYMERS FUNCTIONALIZED WITH POLYIMINE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2009-07-02 | — | — | US | disclosed |