SCHEMBL4258920

SCHEMBL4258920

C=CCN(C=O)C(=O)CO

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27950 0.82 ALDH1A1 (0.40) ALDH1A1SMN1; SMN2
SCHEMBL7487262 0.76
SCHEMBL7995698 0.74
SCHEMBL10385577 0.74
SCHEMBL4087560 0.74 ALDH1A1 (0.37) ALDH1A1
Hydrochloric Acid SCHEMBL11687841 0.74 ALDH1A1 (0.37) ALDH1A1
SCHEMBL5323569 0.74
SCHEMBL6160109 0.73 ALDH1A1 (0.62) ALDH1A1SMN1; SMN2
SCHEMBL7308752 0.71 ALDH1A1 (0.35) ALDH1A1
SCHEMBL11758757 0.70 ALDH1A1 (0.33) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1649861-B1 Adjuvant compositions comprising a mineral salt and another immunostimulating compound SANOFI PASTEUR LTD (CA) 2009-05-13 EP disclosed
EP-1649861-A2 Adjuvant compositions comprising a mineral salt and another immunostimulating compound Sanofi Pasteur Limited (CA) 2006-04-26 EP disclosed
EP-0765163-B8 ADJUVANT COMPOSITIONS COMPRISING A MINERAL SALT AND ANOTHER IMMUNOSTIMULATING COMPOUND SANOFI PASTEUR LTD (CA) 2006-03-08 EP disclosed
EP-0765163-B1 ADJUVANT COMPOSITIONS COMPRISING A MINERAL SALT AND ANOTHER IMMUNOSTIMULATING COMPOUND AVENTIS PASTEUR (CA) 2005-12-07 EP disclosed
US-6764682-B1 IMMUNOMODULATOR MIXTURE OF ALUMINUM HYDROXIDE, ALUMINUM PHOSPHATE, CALCIUM PHOSPHATE, ZINC HYDROXIDE AND/OR CALCIUM HYDROXIDE WITH GLYCOSYLAMIDE AVENTIS PASTEUR LIMITED (CA) 2004-07-20 US disclosed
US-6290971-B1 N-(2-DEOXY-2-L-LEUCYLAMINO-BETA-D-GLUCOPYRANOSYL)-N-OCTADECYL -DODECANAMIDE ACETATE. AVENTIS PASTEUR LIMITED (CA) 2001-09-18 US disclosed
US-5837250-A CONTROLLING IMMUNE RESPONSE; ANTIGEN COMPLEX CONNAUGHT LABORATORIES LIMITED (CA) 1998-11-17 US disclosed
EP-0765163-A2 ADJUVANT COMPOSITIONS COMPRISING A MINERAL SALT AND ANOTHER IMMUNOSTIMULATING COMPOUND Cannaught Laboratories Limited (CA) 1997-04-02 EP disclosed
WO-1995034308-A2 ADJUVANT COMPOSITIONS COMPRISING A MINERAL SALT AND ANOTHER IMMUNOSTIMULATING COMPOUND CONNAUGHT LABORATORIES LIMITED (CA) 1995-12-21 WO disclosed