Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM3B | Q7LBC6 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | DDO | Q99489 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | KDM6B | O15054 | 3/20 | 0.33 |
| ▸ | KDM4A | O75164 | 3/20 | 0.33 |
| ▸ | KDM4D | Q6B0I6 | 3/20 | 0.33 |
| ▸ | HIF1AN | Q9NWT6 | 3/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL425895 | 0.84 | KMT2A (0.49) | KMT2ACYP2C9DDOMAPTKDM4E | |
| SCHEMBL815121 | 0.83 | KDM3B (0.42) | KDM3BKMT2ACYP2C9DDOMAPT | |
| SCHEMBL7545848 | 0.74 | KDM3B (0.46) | KDM3BKMT2ACYP2C9DDOMAPT | |
| SCHEMBL10823650 | 0.69 | KMT2A (0.53) | KMT2ACYP2C9DDOMAPTKDM4E | |
| SCHEMBL5983288 | 0.68 | KMT2A (0.44) | KMT2ACYP2C9DDOMAPTKDM4E | |
| SCHEMBL4950435 | 0.67 | KMT2A (0.50) | KDM3BKMT2ACYP2C9DDOMAPT | |
| SCHEMBL9054602 | 0.67 | KDM3B (0.39) | KDM3BKMT2AMAPTKDM4EGAA | |
| SCHEMBL31282172 | 0.66 | KMT2A (0.49) | KMT2ACYP2C9DDOMAPTKDM4E | |
| SCHEMBL4278691 | 0.66 | PKM (0.38) | ALDH1A1LMNAPKM | |
| SCHEMBL10823643 | 0.66 | HTT (0.56) | KMT2ACYP2C9DDOMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996008559-A1 | GLYCOSAMINOGLYCAN-DEGRADING ENZYME INHIBITION AND RESULTANT DISEASE THERAPIES | CARDIAC CRC NOMINEES PTY. LTD. (AU) | 1996-03-21 | — | — | WO | disclosed |