Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.64 |
| ▸ | GAA | P10253 | 5/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4259031 | 1.00 | ALDH1A1 (0.64) | ALDH1A1GAATDP1MAPTLMNA | |
| SCHEMBL13930637 | 1.00 | ALDH1A1 (0.64) | ALDH1A1GAATDP1MAPTLMNA | |
| SCHEMBL12443527 | 0.78 | ALDH1A1 (1.00) | ALDH1A1GAATDP1MAPTLMNA | |
| SCHEMBL21994252 | 0.76 | ALDH1A1 (0.69) | ALDH1A1GAATDP1MAPTLMNA | |
| SCHEMBL17660221 | 0.73 | RAB9A (0.74) | ALDH1A1GAAMAPTLMNAKDM4E | |
| SCHEMBL22056110 | 0.72 | RAB9A (0.60) | ALDH1A1GAATDP1MAPTLMNA | |
| SCHEMBL29883256 | 0.72 | RAB9A (0.60) | ALDH1A1GAATDP1MAPTLMNA | |
| SCHEMBL940739 | 0.72 | ALDH1A1 (0.64) | ALDH1A1GAATDP1POLBRAB9A | |
| SCHEMBL942207 | 0.72 | ALDH1A1 (0.64) | ALDH1A1GAATDP1POLBRAB9A | |
| SCHEMBL9453890 | 0.71 | ALDH1A1 (0.65) | ALDH1A1GAATDP1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7488721-B2 | Real time methylumbelliferone-based assay | MCMASTER UNIVERSITY (CA) | 2009-02-10 | — | — | US | disclosed |
| US-20060008862-A1 | Real time methylumbelliferone-based assay | THE HOSPITAL FOR SICK CHILDREN | 2006-01-12 | — | — | US | disclosed |