Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | HPGD | P15428 | 2/20 | 0.69 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.69 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.69 |
| ▸ | ABAT | P80404 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.69 |
| ▸ | CA12 | O43570 | 2/20 | 0.62 |
| ▸ | CA4 | P22748 | 2/20 | 0.62 |
| ▸ | CA6 | P23280 | 2/20 | 0.62 |
| ▸ | CA5A | P35218 | 2/20 | 0.62 |
| ▸ | CA7 | P43166 | 2/20 | 0.62 |
| ▸ | CA9 | Q16790 | 2/20 | 0.62 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.62 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.62 |
| ▸ | SHBG | P04278 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TTR | P02766 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Vanillin SCHEMBL28295327 | 0.92 | ALDH1A1 (0.69) | ALDH1A1HPGDTRIM24ALDH5A1ABAT | |
| Vanillin SCHEMBL5529254 | 0.87 | ALDH1A1 (0.71) | ALDH1A1HPGDTRIM24ALDH5A1ABAT | |
| Vanillin SCHEMBL28601372 | 0.87 | ALDH1A1 (0.81) | ALDH1A1HPGDTRIM24ALDH5A1ABAT | |
| Vanillin SCHEMBL19838304 | 0.87 | ALDH1A1 (0.81) | ALDH1A1HPGDTRIM24ALDH5A1ABAT | |
| Vanillin SCHEMBL27845333 | 0.87 | ALDH1A1 (0.93) | ALDH1A1HPGDTRIM24ALDH5A1ABAT | |
| Vanillin SCHEMBL8320727 | 0.85 | ALDH1A1 (0.83) | ALDH1A1HPGDTRIM24ALDH5A1ABAT | |
| Vanillin SCHEMBL29175199 | 0.85 | ALDH1A1 (0.96) | ALDH1A1HPGDTRIM24ALDH5A1ABAT | |
| Vanillin SCHEMBL28865251 | 0.85 | ALDH1A1 (0.68) | ALDH1A1HPGDTRIM24ALDH5A1ABAT | |
| Cis/Trans-Isoeugenol SCHEMBL3968435 | 0.85 | TYR (0.70) | ALDH1A1HPGDTDP1CA12CA4 | |
| Vanillin SCHEMBL14975994 | 0.85 | ALDH1A1 (0.68) | ALDH1A1HPGDTRIM24ALDH5A1ABAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090169652-A1 | Personal Care Compositions | THE PROCTER & GAMBLE COMPANY | 2009-07-02 | — | — | US | disclosed |
| EP-1940346-A2 | COMPOSITION FOR REGULATION OF MAMMALIAN KERATINOUS TISSUE | The Procter and Gamble Company (US) | 2008-07-09 | — | — | EP | disclosed |
| US-20080095731-A1 | Personal Care Compositions Comprising Alpha-Glucans and/or Beta-Glucans | PROCTER & GAMBLE COMPANY, THE | 2008-04-24 | — | — | US | disclosed |
| US-20080075798-A1 | Personal care compositions comprising pear seed extract | PROCTER & GAMBLE COMPANY, THE | 2008-03-27 | — | — | US | disclosed |
| WO-2008027533-A2 | PERSONAL CARE COMPOSITIONS COMPRISING PEAR SEED EXTRACT | THE PROCTER & GAMBLE COMPANY (US) | 2008-03-06 | — | — | WO | disclosed |
| US-20070196296-A1 | Personal care compositions | PROCTER & GAMBLE COMPANY, THE | 2007-08-23 | — | — | US | disclosed |
| US-20070185038-A1 | Regulation of mammalian keratinous tissue using skin care actives | THE PROCTER & GAMBLE COMPANY | 2007-08-09 | — | — | US | disclosed |
| US-20070183993-A1 | Personal care compositions | PROCTER & GAMBLE COMPANY, THE | 2007-08-09 | — | — | US | disclosed |
| WO-2007041548-A2 | COMPOSITION FOR REGULATION OF MAMMALIAN KERATINOUS TISSUE | THE PROCTER & GAMBLE COMPANY (US) | 2007-04-12 | — | — | WO | disclosed |
| WO-2007001904-A2 | PERSONAL CARE COMPOSITIONS COMPRISING ALPHA-GLUCANS AND/OR BETA-GLUCANS | THE PROCTER & GAMBLE COMPANY (US) | 2007-01-04 | — | — | WO | disclosed |
| US-5772909-A | Process for separation of vanillin from other chemicals by means of azeotropic distillation with dibenzyl ether and mixtures of vanillin and dibenzyl ether used in such process | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1998-06-30 | — | — | US | disclosed |
| US-5705703-A | ENZYME INHIBITORS OF TRANSFERASES | HOFFMANN-LA ROCHE INC. (US) | 1998-01-06 | — | — | US | disclosed |
| US-5633371-A | ENZYME INHIBITORS; TREATMENT OF DEPRESSION AND PARKINSON*S DISEASE | HOFFMANN-LA ROCHE INC. (US) | 1997-05-27 | — | — | US | disclosed |
| US-5510006-A | Process for separation of vanillin by means of azeotropic distillation with dibenzyl ether | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1996-04-23 | — | — | US | disclosed |
| US-5476875-A | Catechol derivatives | HOFFMAN-LA ROCHE INC. (US) | 1995-12-19 | — | — | US | disclosed |
| US-5389653-A | Inhibitors of the enzyme catechol-O-methyltransferase; useful as co-medication in treatment of Parkinson's disease | HOFFMAN-LA ROCHE INC. (US) | 1995-02-14 | — | — | US | disclosed |
| US-5236952-A | Inhibit the enzyme catechol-O-methyltransferase; for treatment of Parkinson's disease administered with L-dopa | HOFFMANN-LA ROCHE INC. (US) | 1993-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070196296-A1 | Personal care compositions | CUTA, C5, F7 | ALDH1A1 3550/4885HPGD 1444/4885TRIM24 1291/4885 |
| US-20090169652-A1 | Personal Care Compositions | CUTA, C5, F7 | ALDH1A1 3550/4885HPGD 1444/4885TRIM24 1291/4885 |
| US-20070183993-A1 | Personal care compositions | PPARG, PPARA, PPARD | ALDH1A1 2805/4885HPGD 662/4885TRIM24 1131/4885 |
| US-20080095731-A1 | Personal Care Compositions Comprising Alpha-Glucans and/or Beta-Glucans | HEXA, TYR, HEXB | ALDH1A1 3012/4885HPGD 1021/4885TRIM24 721/4885 |
| US-20080075798-A1 | Personal care compositions comprising pear seed extract | CUTA, POLR1C, DPM1 | ALDH1A1 3508/4885HPGD 3653/4885TRIM24 1277/4885 |
| US-20070185038-A1 | Regulation of mammalian keratinous tissue using skin care actives | CUTA, KDM7A, KDM2A | ALDH1A1 3455/4885HPGD 2220/4885TRIM24 408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.