Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6999185 | 0.88 | L3MBTL1 (0.55) | SMN1; SMN2L3MBTL1KDM4EALDH1A1LMNA | |
| SCHEMBL8900742 | 0.87 | TDP1 (0.59) | SMN1; SMN2L3MBTL1KDM4EALDH1A1LMNA | |
| SCHEMBL4259390 | 0.87 | SMN1; SMN2 (0.56) | SMN1; SMN2L3MBTL1KDM4EALDH1A1LMNA | |
| SCHEMBL7930456 | 0.84 | SMN1; SMN2 (0.66) | SMN1; SMN2L3MBTL1KDM4EALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL658745 | 0.84 | SMN1; SMN2 (0.54) | SMN1; SMN2L3MBTL1KDM4EALDH1A1LMNA | |
| SCHEMBL4239469 | 0.84 | TDP1 (0.57) | SMN1; SMN2L3MBTL1KDM4EALDH1A1LMNA | |
| SCHEMBL8260310 | 0.83 | ALDH1A1 (0.53) | SMN1; SMN2L3MBTL1KDM4EALDH1A1LMNA | |
| SCHEMBL2555975 | 0.81 | TDP1 (0.73) | SMN1; SMN2L3MBTL1KDM4EALDH1A1LMNA | |
| SCHEMBL20328289 | 0.80 | CNR1 (0.57) | SMN1; SMN2L3MBTL1KDM4EALDH1A1LMNA | |
| SCHEMBL10886971 | 0.79 | POLB (0.51) | SMN1; SMN2L3MBTL1ALDH1A1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1846430-B1 | NEW MACROLIDES | BASILEA PHARMACEUTICA AG (CH) | 2009-04-01 | — | — | EP | disclosed |