SCHEMBL425944

SCHEMBL425944

[CH2]S(=O)(=O)NC(C)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1751665 0.75
SCHEMBL3310419 0.73 CA2 (0.41)
SCHEMBL10025586 0.73
SCHEMBL208791 0.71
SCHEMBL177789 0.71
Ethylene SCHEMBL27432797 0.71 DHFR (0.34)
SCHEMBL724276 0.69
SCHEMBL3284719 0.69
SCHEMBL4266233 0.69
SCHEMBL1618240 0.69 CA2 (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0480659-B1 Use of Angiotensin-II antagonists for the manufacture of a medicament for the treatment of hyperuricemia MERCK & CO INC (US) 1996-09-04 EP claimed
CN-104245681-B (1,2, 3-Azole) sulfonyl derivatives 南京优迪生物医药有限公司 2017-09-26 CN disclosed
EP-2751084-B1 PYRIMIDINE CARBOXAMIDE DERIVATIVES EUDIS BIOTECH LLC (CN) 2016-09-21 EP disclosed
US-9249107-B2 Pyrimidine carboxamide derivatives MAEHR HUBERT (US) 2016-02-02 US disclosed
US-20150087665-A1 Pyrimidine carboxamide derivatives Maehr, Hubert (US) 2015-03-26 US disclosed
EP-2834223-A2 (1,2,3-TRIAZOLYL) SULFONYL DERIVATIVES Apac Pharmaceutical LLC. (US) 2015-02-11 EP disclosed
US-8853248-B2 (1,2,3-triazolyl)sulfonyl derivatives MAEHR HUBERT (US) 2014-10-07 US disclosed
EP-2751084-A1 PYRIMIDINE CARBOXAMIDE DERIVATIVES Apac Pharmaceutical LLC. (US) 2014-07-09 EP disclosed
US-8580805-B2 Pyrimidine carboxamide derivatives MAEHR HUBERT (US) 2013-11-12 US disclosed
WO-2013151597-A2 (1,2,3-TRIAZOLYL) SULFONYL DERIVATIVES APAC PHARMACEUTICAL LLC. (US) 2013-10-10 WO disclosed
EP-1067430-A1 Silver halide photographic emulsion and photographic light-sensitive material using the same FUJI PHOTO FILM CO., LTD. (JP) 2001-01-10 EP disclosed
EP-1061411-A1 Silver halide photographic emulsion and photographic light-sensitive material using the same FUJI PHOTO FILM CO., LTD. (JP) 2000-12-20 EP disclosed
US-6117629-A SILVER HALIDE GRAINS HAVING A LIGHT ABSORPTION STRENGTH OF 100 OR MORE PER UNIT SURFACE AREA, WHEREIN THE SILVER HALIDE GRAINS HAVE BEEN SPECTRALLY SENSITIZED WITH A SENSITIZING DYE THAT IS MULTILAYER ADSORBED ONTO A SURFACE OF THE GRAINS FUJI PHOTO FILM CO., LTD. (JP) 2000-09-12 US disclosed
US-5928854-A QUATERNIZED METHINE DYE; HIGH LIGHT ABSORPTION; COLOR PHOTOGRAPHY FUJI PHOTO FILM CO., LTD. (JP) 1999-07-27 US disclosed
EP-0905558-A1 Photographic silver halide emulsion KONICA CORPORATION (JP) 1999-03-31 EP disclosed
US-5885764-A SPECTRAL SENSITIVITY FUJI PHOTO FILM CO., LTD. (JP) 1999-03-23 US disclosed
EP-0838719-A2 Silver halide photographic emulsion and silver halide photographic material containing said silver halide photographic emulsion FUJI PHOTO FILM CO., LTD. (JP) 1998-04-29 EP disclosed
EP-0480659-B1 Use of Angiotensin-II antagonists for the manufacture of a medicament for the treatment of hyperuricemia MERCK & CO INC (US) 1996-09-04 EP disclosed
US-5260322-A Angiotension II antagonists in the treatment of hyperuricemia MERCK & CO., INC. (US) 1993-11-09 US disclosed
EP-0480659-A2 Use of Angiotensin-II antagonists for the manufacture of a medicament for the treatment of hyperuricemia MERCK & CO. INC. (US) 1992-04-15 EP disclosed