Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.71 |
| ▸ | RAB9A | P51151 | 4/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | FAAH | O00519 | 12/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4259708 | 1.00 | NPC1 (0.71) | NPC1RAB9AMEN1KMT2AFAAH | |
| SCHEMBL4409065 | 0.86 | FAAH (0.58) | NPC1RAB9AMEN1KMT2AFAAH | |
| SCHEMBL4409062 | 0.86 | FAAH (0.58) | NPC1RAB9AMEN1KMT2AFAAH | |
| SCHEMBL13930606 | 0.86 | FAAH (0.58) | NPC1RAB9AMEN1KMT2AFAAH | |
| SCHEMBL4259699 | 0.78 | PLA2G7 (0.73) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL4259696 | 0.78 | PLA2G7 (0.73) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL11151343 | 0.72 | RAB9A (0.59) | NPC1RAB9AMEN1KMT2AFAAH | |
| SCHEMBL31060223 | 0.70 | FAAH (1.00) | FAAH | |
| SCHEMBL11162837 | 0.69 | FAAH (0.60) | NPC1RAB9AMEN1KMT2AFAAH | |
| SCHEMBL22103765 | 0.69 | RAB9A (0.72) | NPC1RAB9AMEN1KMT2AFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7488721-B2 | Real time methylumbelliferone-based assay | MCMASTER UNIVERSITY (CA) | 2009-02-10 | — | — | US | disclosed |
| US-7488721-B2 | Real time methylumbelliferone-based assay | MCMASTER UNIVERSITY (CA) | 2009-02-10 | — | — | US | disclosed |
| US-7488721-B2 | Real time methylumbelliferone-based assay | MCMASTER UNIVERSITY (CA) | 2009-02-10 | — | — | US | disclosed |