Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.52 |
| ▸ | AGXT | P21549 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | APP | P05067 | 7/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4259907 | 0.85 | CA1 (0.49) | IDO1AGXTCA1CA2APP | |
| SCHEMBL52777 | 0.84 | IDO1 (0.59) | IDO1AGXTCA1CA2APP | |
| SCHEMBL34413 | 0.81 | IDO1 (0.67) | IDO1AGXTCA1CA2APP | |
| SCHEMBL1475481 | 0.79 | IDO1 (0.64) | IDO1AGXTCA1CA2APP | |
| Potassium SCHEMBL1477050 | 0.79 | IDO1 (0.64) | IDO1AGXTCA1CA2APP | |
| SCHEMBL8499580 | 0.77 | IDO1 (0.61) | IDO1AGXTCA1CA2APP | |
| SCHEMBL2618879 | 0.75 | IDO1 (0.59) | IDO1AGXTCA1CA2APP | |
| SCHEMBL11132720 | 0.75 | LTA4H (0.65) | IDO1AGXTCA1CA2APP | |
| SCHEMBL11132718 | 0.75 | IDO1 (0.59) | IDO1AGXTCA1CA2APP | |
| SCHEMBL15112891 | 0.74 | IDO1 (0.48) | IDO1AGXTCA1CA2APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009046098-A1 | NOVEL CYCLIC BORONATE INHIBITORS OF HCV REPLICATION | SMITHKLINE BEECHAM CORPORATION (US) | 2009-04-09 | — | — | WO | disclosed |