Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20241100 | 0.77 | GAA (0.55) | KDM4EALDH1A1HPGDMAPK1RECQL | |
| SCHEMBL3535665 | 0.72 | KDM4E (0.50) | KDM4EALDH1A1HPGDMAPK1RECQL | |
| SCHEMBL16291562 | 0.69 | EDNRA (0.55) | KDM4EALDH1A1HPGDMAPK1RECQL | |
| SCHEMBL4259979 | 0.69 | KDM4E (0.82) | KDM4EALDH1A1HPGDMAPK1RECQL | |
| SCHEMBL2402149 | 0.68 | ANO1 (0.44) | KDM4EALDH1A1HPGDMAPK1RECQL | |
| SCHEMBL10372054 | 0.66 | ALDH1A1 (0.67) | KDM4EALDH1A1RECQLMEN1KMT2A | |
| SCHEMBL14327977 | 0.65 | L3MBTL1 (0.64) | KDM4EALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL10506317 | 0.65 | SMN1; SMN2 (0.60) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL3536870 | 0.65 | ALDH1A1 (0.63) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL10193137 | 0.65 | PPARD (0.59) | KDM4EALDH1A1HPGDHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7488721-B2 | Real time methylumbelliferone-based assay | MCMASTER UNIVERSITY (CA) | 2009-02-10 | — | — | US | disclosed |