Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 7/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 7/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 7/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 7/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 7/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4256948 | 0.89 | PSEN1 (0.42) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL4261403 | 0.89 | MAPT (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL4267813 | 0.87 | SIGMAR1 (0.38) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL4262345 | 0.85 | TSPO (0.41) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL4254311 | 0.82 | PSEN1 (0.38) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL4267934 | 0.82 | MAPT (0.42) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL5999369 | 0.82 | MAPT (0.49) | MAPTPOLBLMNAHTTALDH1A1 | |
| SCHEMBL4971891 | 0.80 | PSEN1 (0.31) | PSEN1 | |
| SCHEMBL4260565 | 0.80 | MAPT (0.35) | MAPTPOLBHPGDLMNASMN1; SMN2 | |
| SCHEMBL4267403 | 0.78 | MAPT (0.39) | PSEN1MAPTPOLBALDH1A1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090242876-A1 | CARBAZOLE COMPOUNDS | KONINKLIJKE PHILIPS ELECTRONICS, N.V. (NL) | 2009-10-01 | — | — | US | disclosed |
| US-20080269461-A1 | Polymeric Carbazole Compounds | KONINKLIJKE PHILIPS ELECTRONICS, N.V. (NL) | 2008-10-30 | — | — | US | disclosed |
| EP-1966270-A1 | POLYMERIC CARBAZOLE COMPOUNDS | Koninklijke Philips Electronics N.V. (NL) | 2008-09-10 | — | — | EP | disclosed |
| EP-1838671-B1 | 9,9'- AND 2,2'-SUBSTITUTED 3,3'-BICARBAZOLYL DERIVATIVES FOR USE IN SEMICONDUCTING MATERIALS AS A HOST MATRIX FOR PHOSPHORESCENT EMITTERS | KONINKL PHILIPS ELECTRONICS NV (NL) | 2008-06-04 | — | — | EP | disclosed |
| EP-1838671-A2 | 9,9'- AND 2,2'-SUBSTITUTED 3,3'-BICARBAZOLYL DERIVATIVES FOR USE IN SEMICONDUCTING MATERIALS AS A HOST MATRIX FOR PHOSPHORESCENT EMITTERS | Koninklijke Philips Electronics N.V. (NL) | 2007-10-03 | — | — | EP | disclosed |
| WO-2007072240-A1 | POLYMERIC CARBAZOLE COMPOUNDS | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 2007-06-28 | — | — | WO | disclosed |
| WO-2006061759-A2 | 9 , 9 ' - AND 2 , 2 ' -SUBSTITUTED 3 , 3 ' -BICARBAZOLYL DERIVATIVES FOR USE IN SEMICONDUCTING MATERIALS AS A HOST MATRIX FOR PHOSPHORESCENT EMITTERS | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 2006-06-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090242876-A1 | CARBAZOLE COMPOUNDS | CCNI, IL33, PAICS | PSEN1 3440/4885PSEN2 3310/4885APH1B 1015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.