SCHEMBL4260933

SCHEMBL4260933

CC(=O)c1ccc(C=S)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.48
HPGD P15428 4/20 0.48
RAB9A P51151 4/20 0.48
LMNA P02545 3/20 0.48
L3MBTL1 Q9Y468 3/20 0.48
KMT2A Q03164 2/20 0.48
SMN1; SMN2 Q16637 3/20 0.46
HSD17B1 P14061 1/20 0.46
MAPK1 P28482 2/20 0.43
NOS3 P29474 2/20 0.43
NOS1 P29475 2/20 0.43
NPC1 O15118 3/20 0.42
ALDH1A1 P00352 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
STAT3 P40763 1/20 0.42
STAT1 P42224 1/20 0.42
GLA P06280 1/20 0.41
POLB P06746 1/20 0.41
GAA P10253 1/20 0.41
TAAR1 Q96RJ0 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8589167 0.80 LMNA (0.53) MAPTHPGDRAB9ALMNAL3MBTL1
SCHEMBL8583468 0.80 HPGD (0.52) MAPTHPGDRAB9ALMNAL3MBTL1
SCHEMBL7506335 0.80 SRD5A2 (0.48) MAPTHPGDRAB9ALMNAL3MBTL1
SCHEMBL8589165 0.80 LMNA (0.53) MAPTHPGDRAB9ALMNAL3MBTL1
SCHEMBL50646 0.79 MAPT (0.68) MAPTHPGDRAB9ALMNAL3MBTL1
SCHEMBL566777 0.79 LMNA (0.45) MAPTHPGDRAB9ALMNAL3MBTL1
SCHEMBL566778 0.79 LMNA (0.45) MAPTHPGDRAB9ALMNAL3MBTL1
SCHEMBL315780 0.78 ALDH1A1 (0.62) MAPTHPGDL3MBTL1KMT2ASMN1; SMN2
SCHEMBL97268 0.78 ALDH1A1 (0.62) MAPTHPGDRAB9ALMNAL3MBTL1
SCHEMBL25304810 0.76 LMNA (0.50) MAPTHPGDRAB9ALMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0444168-A1 PROCESS FOR REDUCING THE SWELLABILITY OF STARCHES FLUNTERA AG (CH) 1991-09-04 EP claimed
WO-1991004278-A1 PROCESS FOR REDUCING THE SWELLABILITY OF STARCHES TOMKA IVAN (CH) 1991-04-04 WO claimed
US-4582903-A Synthesis of unsaturated hydantoins with an inexpensive catalyst STAUFFER CHEMICAL COMPANY (US) 1986-04-15 US claimed
US-7518905-B2 High density memory device THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-04-14 US disclosed
US-20060209587-A1 High density memory device THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2006-09-21 US disclosed
US-7061791-B2 High density molecular memory device THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2006-06-13 US disclosed
US-7042755-B1 High density non-volatile memory device THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2006-05-09 US disclosed
EP-1210714-A4 HIGH DENSITY NON-VOLATILE MEMORY DEVICE UNIV (US) 2006-01-04 EP disclosed
US-20050041494-A1 High density non-volatile memory device THE REGENTS OF THE UNIVERSITY OF CALIFORNIA AND NORTH CAROLINA STATE UNIVERSITY 2005-02-24 US disclosed
US-6657884-B2 High density non-volatile memory device THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2003-12-02 US disclosed
US-20020154535-A1 High density non-volatile memory device THE REGENTS OF THE UNIVERSITY OF CALIFORNIA OFFICE OF TECHNOLOGY TRANSFER 2002-10-24 US disclosed
EP-0444168-A1 PROCESS FOR REDUCING THE SWELLABILITY OF STARCHES FLUNTERA AG (CH) 1991-09-04 EP disclosed
WO-1991004278-A1 PROCESS FOR REDUCING THE SWELLABILITY OF STARCHES TOMKA IVAN (CH) 1991-04-04 WO disclosed
US-4994623-A Process for producing thioalkyl or thioarylphenones HOECHST CELANESE CORPORATION (US) 1991-02-19 US disclosed
US-4684735-A Promotion of raney nickel hydrogenation catalyst STAUFFER CHEMICAL COMPANY (US) 1987-08-04 US disclosed
US-4650876-A INCREMENTAL ADDITION TO PREVENT FOAMING, RANEY CATALYST STAUFFER CHEMICAL COMPANY (US) 1987-03-17 US disclosed
EP-0210683-A1 Promotion of raney nickel catalyst STAUFFER CHEMICAL COMPANY (US) 1987-02-04 EP disclosed
US-4613691-A Preparation of amino acids from unsaturated hydantoins STAUFFER CHEMICAL COMPANY (US) 1986-09-23 US disclosed
US-4582903-A Synthesis of unsaturated hydantoins with an inexpensive catalyst STAUFFER CHEMICAL COMPANY (US) 1986-04-15 US disclosed
EP-0177072-A2 Preparation of amino acids from unsaturated hydantoins STAUFFER CHEMICAL COMPANY (US) 1986-04-09 EP disclosed