Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9129258 | 0.78 | CYP3A4 (0.44) | CYP3A4CYP2C19GAASLC6A2SLC6A4 | |
| SCHEMBL18812091 | 0.76 | CYP3A4 (0.43) | CYP3A4CYP2C19GAASLC6A2SLC6A4 | |
| SCHEMBL4266708 | 0.75 | KMT2A (0.42) | CYP3A4CYP2C19SLC6A4SLC6A3KMT2A | |
| SCHEMBL33167 | 0.71 | — | — | |
| SCHEMBL724559 | 0.71 | CYP3A4 (0.52) | CYP3A4CYP2C19GAASLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL28532113 | 0.69 | CYP3A4 (0.50) | CYP3A4CYP2C19GAASLC6A2SLC6A4 | |
| SCHEMBL27723381 | 0.69 | CYP3A4 (0.50) | CYP3A4CYP2C19GAASLC6A2SLC6A4 | |
| SCHEMBL29452917 | 0.69 | CYP3A4 (0.50) | CYP3A4CYP2C19GAASLC6A2SLC6A4 | |
| SCHEMBL27359967 | 0.69 | CYP3A4 (0.50) | CYP3A4CYP2C19GAASLC6A2SLC6A4 | |
| SCHEMBL21325964 | 0.69 | CYP3A4 (0.36) | CYP3A4CYP2C19GAASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1742635-A2 | SUBSTITUTED ORGANOSULFUR COMPOUNDS AND METHODS OF USING THEREOF | Acea Biosciences, Inc. (US) | 2007-01-17 | — | — | EP | claimed |
| WO-2005112933-A2 | SUBSTITUTED ORGANOSULFUR COMPOUNDS AND METHODS OF USING THEREOF | ACEA BIOSCIENCES INC. (US) | 2005-12-01 | — | — | WO | claimed |
| US-20050261321-A1 | Substituted organosulfur compounds and methods of using thereof | ACEA Therapeutics, Inc. | 2005-11-24 | — | — | US | claimed |
| EP-1742635-B1 | SUBSTITUTED ORGANOSULFUR COMPOUNDS AND METHODS OF USING THEREOF | ACEA BIOSCIENCES INC (US) | 2018-03-07 | — | — | EP | disclosed |
| US-8334316-B2 | Substituted organosulfur compounds and methods of using thereof | ACEA BIOSCIENCES, INC. (US) | 2012-12-18 | — | — | US | disclosed |
| US-7622507-B2 | Substituted organosulfur compounds and methods of using thereof | ACEA BIOSCIENCES INC. (US) | 2009-11-24 | — | — | US | disclosed |
| US-20090192146-A1 | SUBSTITUTED ORGANOSULFUR COMPOUNDS AND METHODS OF USING THEREOF | ACEA BIOSCIENCES, INC. (US) | 2009-07-30 | — | — | US | disclosed |
| EP-1742635-A2 | SUBSTITUTED ORGANOSULFUR COMPOUNDS AND METHODS OF USING THEREOF | Acea Biosciences, Inc. (US) | 2007-01-17 | — | — | EP | disclosed |
| WO-2005112933-A2 | SUBSTITUTED ORGANOSULFUR COMPOUNDS AND METHODS OF USING THEREOF | ACEA BIOSCIENCES INC. (US) | 2005-12-01 | — | — | WO | disclosed |
| US-20050261321-A1 | Substituted organosulfur compounds and methods of using thereof | ACEA Therapeutics, Inc. | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192146-A1 | SUBSTITUTED ORGANOSULFUR COMPOUNDS AND METHODS OF USING THEREOF | TST, CTH, CBS | CYP3A4 3786/4885CYP2C19 4138/4885GAA 2926/4885 |
| US-20050261321-A1 | Substituted organosulfur compounds and methods of using thereof | TST, CTH, CBS | CYP3A4 3786/4885CYP2C19 4138/4885GAA 2926/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.