SCHEMBL426173

SCHEMBL426173

CC(CCCO)CC(=O)O

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
BHMT Q93088 1/20 0.44
CAMK2A Q9UQM7 1/20 0.40
BLM P54132 1/20 0.39
GPR84 Q9NQS5 5/20 0.38
FFAR1 O14842 1/20 0.37
FFAR4 Q5NUL3 1/20 0.37
ACE2 Q9BYF1 1/20 0.36
SLC22A6 Q4U2R8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18704287 1.00 BHMT (0.44) BHMTCAMK2ABLMGPR84FFAR1
SCHEMBL9460828 1.00 BHMT (0.44) BHMTCAMK2ABLMGPR84FFAR1
SCHEMBL8569864 0.93 BHMT (0.43) BHMTCAMK2ABLMGPR84FFAR1
SCHEMBL8984477 0.91 GPR84 (0.44) BHMTCAMK2ABLMGPR84FFAR1
SCHEMBL8984580 0.91 GPR84 (0.44) BHMTCAMK2ABLMGPR84FFAR1
SCHEMBL8984636 0.91 GPR84 (0.44) BHMTCAMK2ABLMGPR84FFAR1
SCHEMBL8984397 0.91 GPR84 (0.44) BHMTCAMK2ABLMGPR84FFAR1
SCHEMBL14360558 0.87 BHMT (0.48) BHMTBLMGPR84ACE2SLC22A6
SCHEMBL425046 0.87 BHMT (0.48) BHMTBLMGPR84ACE2SLC22A6
SCHEMBL7532145 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113004205-B PPAR agonists, compounds, pharmaceutical compositions, and methods of use thereof 米托布里奇公司 2024-07-02 CN disclosed
US-11912681-B2 Crystalline and salt forms of PPAR agonist compounds MITOBRIDGE, INC. (US) 2024-02-27 US disclosed
US-20230373948-A1 PPAR AGONISTS, COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF Astellas Engineered Small Molecules US, Incorporated 2023-11-23 US disclosed
US-20230257360-A1 CRYSTALLINE AND SALT FORMS OF PPAR AGONIST COMPOUNDS Astellas Engineered Small Molecules US, Incorporated 2023-08-17 US disclosed
EP-3795566-B1 PPAR AGONISTS, COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF MITOBRIDGE INC (US) 2023-04-19 EP disclosed
US-11578052-B2 PPAR agonists, compounds, pharmaceutical compositions, and methods of use thereof MITOBRIDGE, INC. (US) 2023-02-14 US disclosed
CN-109843857-B Crystalline and salt forms of PPAR agonist compounds 米托布里奇公司 2023-01-06 CN disclosed
US-11530192-B2 Crystalline and salt forms of PPAR agonist compounds MITOBRIDGE, INC. (US) 2022-12-20 US disclosed
CN-109789117-B Method for treating acute kidney injury 米托布里奇公司 2022-08-23 CN disclosed
CN-109071459-B PPAR agonists, compounds, pharmaceutical compositions, and methods of use thereof 米托布里奇公司 2022-08-16 CN disclosed
EP-1622962-B1 TOUGHENED POLYOXYMETHYLENE-POLY(LACTIC ACID) COMPOSITIONS DU PONT (US) 2006-07-05 EP disclosed
EP-1622962-A1 TOUGHENED POLYOXYMETHYLENE-POLY(LACTIC ACID) COMPOSITIONS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2006-02-08 EP disclosed
CN-1701082-A Toughened polyoxymethylene-poly(lactic acid) compositions DU PONT (US) 2005-11-23 CN disclosed
US-6943214-B2 Toughened polyoxymethylene-poly(lactic acid) compositions E. I. DU PONT DE NEMOURS AND COMPANY (US) 2005-09-13 US disclosed
WO-2005059031-A1 TOUGHENED POLY(LACTIC ACID) COMPOSITIONS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2005-06-30 WO disclosed
US-20050131120-A1 Toughened poly(lactic acid) compositions PERFORMANCE MATERIALS NA, INC. 2005-06-16 US disclosed
WO-2004101642-A1 TOUGHENED POLYOXYMETHYLENE-POLY(LACTIC ACID) COMPOSITIONS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2004-11-25 WO disclosed
US-20040230001-A1 Toughened polyoxymethylene-poly(lactic acid) compositions GOLDMAN SACHS BANK USA, AS COLLATERAL AGENT 2004-11-18 US disclosed
US-5227090-A Acrylic ester polymers HOECHST AKTIENGESELLSCHAFT (DE) 1993-07-13 US disclosed
US-4140712-A 20-Hydroxy-prostaglandins ONO PHARMACEUTICAL COMPANY (JP) 1979-02-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11530192-B2 Crystalline and salt forms of PPAR agonist compounds PPARD, PPARA, PPARG BHMT 4414/4885CAMK2A 706/4885BLM 3293/4885
US-11912681-B2 Crystalline and salt forms of PPAR agonist compounds PPARD, PPARA, PPARG BHMT 4414/4885CAMK2A 706/4885BLM 3293/4885
US-20230373948-A1 PPAR AGONISTS, COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF PPARG, PPARD, PPARA BHMT 2630/4885CAMK2A 1276/4885BLM 2009/4885
US-11578052-B2 PPAR agonists, compounds, pharmaceutical compositions, and methods of use thereof PPARG, PPARD, PPARA BHMT 2630/4885CAMK2A 1276/4885BLM 2009/4885
US-20230257360-A1 CRYSTALLINE AND SALT FORMS OF PPAR AGONIST COMPOUNDS PPARD, PPARA, PPARG BHMT 4414/4885CAMK2A 706/4885BLM 3293/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.