⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5501839 | 1.00 | — | — | |
| SCHEMBL12287911 | 1.00 | — | — | |
| SCHEMBL8009888 | 0.89 | TSHR (0.44) | — | |
| SCHEMBL9974590 | 0.86 | BHMT (0.52) | — | |
| SCHEMBL9460828 | 0.85 | BHMT (0.44) | — | |
| SCHEMBL426173 | 0.85 | BHMT (0.44) | — | |
| SCHEMBL18704287 | 0.85 | BHMT (0.44) | — | |
| SCHEMBL8569864 | 0.83 | BHMT (0.43) | — | |
| Ethylene Glycol SCHEMBL10361806 | 0.83 | GABRP (0.48) | — | |
| Toluene SCHEMBL28231458 | 0.82 | TRPA1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240180941-A1 | ACTIVE AGENTS AND METHODS OF THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS AND NONALCOHOLIC FATTY LIVER DISEASE | FLAGSHIP PIONEERING INNOVATIONS V INC (US) | 2024-06-06 | — | — | US | disclosed |
| US-11813272-B2 | Active agents and methods of their use for the treatment of metabolic disorders and nonalcoholic fatty liver disease | FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) | 2023-11-14 | — | — | US | disclosed |
| US-20230293458-A1 | MULTIBIOTIC AGENTS AND METHODS OF USING THE SAME | FLAGSHIP PIONEERING INNOVATIONS V INC (US) | 2023-09-21 | — | — | US | disclosed |
| US-20210177877-A1 | ACTIVE AGENTS AND METHODS OF THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS AND NONALCOHOLIC FATTY LIVER DISEASE | FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) | 2021-06-17 | — | — | US | disclosed |
| US-10953027-B2 | Active agents and methods of their use for the treatment of metabolic disorders and nonalcoholic fatty liver disease | FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) | 2021-03-23 | — | — | US | disclosed |
| US-20200197428-A1 | ACTIVE AGENTS AND METHODS OF THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS AND NONALCOHOLIC FATTY LIVER DISEASE | FLAGSHIP PIONEERING, INC. | 2020-06-25 | — | — | US | disclosed |
| US-20200101030-A1 | MULTIBIOTIC AGENTS AND METHODS OF USING THE SAME | KINTAI THERAPEUTICS, INC. | 2020-04-02 | — | — | US | disclosed |
| EP-2498605-B1 | DIURETICS | MERCK SHARP & DOHME (US) | 2014-08-27 | — | — | EP | disclosed |
| CN-102167666-B | Method for synthesizing high-enantiomer-purity diprionidae pheromone and stereo isomer | UNIV XIAMEN | 2013-09-18 | — | — | CN | disclosed |
| US-8354394-B2 | Diuretics | MERCK SHARP & DOHME CORP. (US) | 2013-01-15 | — | — | US | disclosed |
| US-20120208838-A1 | DIURETICS | MERCK SHARP & DOHME LLC | 2012-08-16 | — | — | US | disclosed |
| CN-102167666-A | Method for synthesizing high-enantiomer-purity diprionidae pheromone and stereo isomer | UNIV XIAMEN | 2011-08-31 | — | — | CN | disclosed |
| CN-101210258-A | Method for preparing (R)-3-hydroxyethyl butyrate by microorganism conversion | UNIV ZHEJIANG TECHNOLOGY (CN) | 2008-07-02 | — | — | CN | disclosed |
| CN-1205250-C | Polymerization of ethylene oxide using metal cyanide catalysts | DOW GLOBAL TECHNOLOGY INC (US) | 2005-06-08 | — | — | CN | disclosed |
| CN-1360607-A | Polymerization of ethylene oxide using metal cyanide catalysts | DOW CHEMICAL CO (US) | 2002-07-24 | — | — | CN | disclosed |
| EP-1188749-A1 | PROCESS FOR THE PREPARATION OF INTERMEDIATE COMPOUNDS OF DRUGS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-03-20 | — | — | EP | disclosed |