SCHEMBL4262292

SCHEMBL4262292

COC(=O)COc1ccc(-c2coc3cc(OCC(=O)OC)c(OC)cc3c2=O)cc1

nearest known ligand 0.66

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.66
ALDH1A1 P00352 2/20 0.66
RAB9A P51151 2/20 0.59
KLK7 P49862 1/20 0.59
HDAC6 Q9UBN7 1/20 0.55
ALDH2 P05091 2/20 0.54
ACHE P22303 3/20 0.53
GAA P10253 1/20 0.53
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
POLB P06746 1/20 0.52
NPC1 O15118 1/20 0.52
PTPN1 P18031 1/20 0.52
PPARG P37231 1/20 0.52
HPGD P15428 1/20 0.50
XDH P47989 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4264740 0.96 RAB9A (0.65) MAPTALDH1A1RAB9AKLK7HDAC6
SCHEMBL15341741 0.89 MAPT (0.66) MAPTALDH1A1RAB9AKLK7HDAC6
SCHEMBL15341731 0.86 MAPT (0.61) MAPTALDH1A1RAB9AKLK7HDAC6
SCHEMBL4095148 0.85 MAPT (0.87) MAPTALDH1A1RAB9AHDAC6ALDH2
SCHEMBL4410790 0.85 ALDH2 (0.58) MAPTALDH1A1RAB9AKLK7HDAC6
SCHEMBL4261437 0.82 MAPT (0.80) MAPTALDH1A1RAB9AHDAC6ALDH2
SCHEMBL30573375 0.81 RAB9A (0.81) MAPTALDH1A1RAB9AKLK7HDAC6
SCHEMBL7030328 0.81 RAB9A (0.81) MAPTALDH1A1RAB9AKLK7HDAC6
SCHEMBL4277128 0.79 MAPT (1.00) MAPTALDH1A1RAB9AHDAC6ALDH2
SCHEMBL11344171 0.78 HDAC6 (0.85) MAPTALDH1A1RAB9AKLK7HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8802892-B2 Functionalized phenolic compounds and polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2014-08-12 US disclosed
US-8802892-B2 Functionalized phenolic compounds and polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2014-08-12 US disclosed
US-20130281652-A1 FUNCTIONALIZED PHENOLIC COMPOUNDS AND POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC 2013-10-24 US disclosed
US-20130281652-A1 FUNCTIONALIZED PHENOLIC COMPOUNDS AND POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC 2013-10-24 US disclosed
US-8318973-B2 Functionalized sinapic acid and methyl sinapate BEZWADA BIOMEDICAL, LLC (US) 2012-11-27 US disclosed
US-8318973-B2 Functionalized sinapic acid and methyl sinapate BEZWADA BIOMEDICAL, LLC (US) 2012-11-27 US disclosed
US-8318973-B2 Functionalized sinapic acid and methyl sinapate BEZWADA BIOMEDICAL, LLC (US) 2012-11-27 US disclosed
US-20090170927-A1 FUNCTIONALIZED PHENOLIC COMPOUNDS AND POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2009-07-02 US disclosed
US-20090170927-A1 FUNCTIONALIZED PHENOLIC COMPOUNDS AND POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2009-07-02 US disclosed
US-20090170927-A1 FUNCTIONALIZED PHENOLIC COMPOUNDS AND POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2009-07-02 US disclosed
WO-2007053794-A2 FUNCTIONALIZED PHENOLIC COMPOUNDS AND ABSORBABLE THEREFROM BEZWADA BIOMEDICAL LLC (US) 2007-05-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090170927-A1 FUNCTIONALIZED PHENOLIC COMPOUNDS AND POLYMERS THEREFROM COMT, AOX1, UGT1A6 MAPT 2351/4885ALDH1A1 384/4885RAB9A 3005/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.