Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | BLM | P54132 | 2/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.60 |
| ▸ | HTR2C | P28335 | 2/20 | 0.60 |
| ▸ | HTR1A | P08908 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | HTR7 | P34969 | 1/20 | 0.60 |
| ▸ | HTR2B | P41595 | 1/20 | 0.60 |
| ▸ | MTOR | P42345 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4262934 | 1.00 | HTR2A (0.60) | HTR2AKMT2ATSHRSLC6A4KDM4E | |
| SCHEMBL30405928 | 0.89 | KMT2A (0.73) | HTR2AKMT2ATSHRSLC6A4KDM4E | |
| SCHEMBL19871231 | 0.89 | KMT2A (0.73) | HTR2AKMT2ATSHRSLC6A4KDM4E | |
| SCHEMBL307776 | 0.89 | KMT2A (0.73) | HTR2AKMT2ATSHRSLC6A4KDM4E | |
| SCHEMBL454983 | 0.89 | KMT2A (0.73) | HTR2AKMT2ATSHRSLC6A4KDM4E | |
| SCHEMBL5493779 | 0.89 | KMT2A (0.73) | HTR2AKMT2ATSHRSLC6A4KDM4E | |
| SCHEMBL29382361 | 0.89 | KMT2A (0.73) | HTR2AKMT2ATSHRSLC6A4KDM4E | |
| SCHEMBL248870 | 0.89 | KMT2A (0.66) | HTR2AKMT2ATSHRSLC6A4KDM4E | |
| SCHEMBL2330930 | 0.89 | KMT2A (0.66) | HTR2AKMT2ATSHRSLC6A4KDM4E | |
| SCHEMBL30381733 | 0.89 | KMT2A (0.66) | HTR2AKMT2ATSHRSLC6A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090023139-A1 | Method For Site-Specifically Introducing Non-Natural Amino Acid Into Protien Using Mitochondrial Protein and Method For Effectively Preparing Trna | GIFU UNIVERSITY (JP) | 2009-01-22 | — | — | US | disclosed |
| EP-1818400-A1 | METHOD OF SITE-SPECIFICALLY INTRODUCING NON-NATURAL AMINO ACID INTO PROTEIN USING MITOCHONDRIAL PROTEIN AND METHOD FOR EFFECTIVELY PREPARING tRNA | Gifu University (JP) | 2007-08-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023139-A1 | Method For Site-Specifically Introducing Non-Natural Amino Acid Into Protien Using Mitochondrial Protein and Method For Effectively Preparing Trna | FARS2, MARS2, AARS1 | HTR2A 702/4885KMT2A 1779/4885TSHR 1649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.