SCHEMBL4263171

SCHEMBL4263171

CC(C)(c1ccccc1)c1ccccc1Br

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.45
ESR1 P03372 2/20 0.45
ESR2 Q92731 2/20 0.45
CYP3A4 P08684 1/20 0.45
MAPK1 P28482 2/20 0.39
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA5A P35218 1/20 0.38
CA9 Q16790 1/20 0.38
TAAR1 Q96RJ0 1/20 0.37
ALOX15 P16050 1/20 0.37
HDAC3 O15379 1/20 0.36
HDAC4 P56524 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC7 Q8WUI4 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC10 Q969S8 1/20 0.36
HDAC11 Q96DB2 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29395631 1.00 ALDH1A1 (0.45) ALDH1A1ESR1ESR2CYP3A4MAPK1
SCHEMBL28655742 0.85 ALDH1A1 (0.43) ALDH1A1ESR1ESR2CYP3A4MAPK1
SCHEMBL2199266 0.83 ALDH1A1 (0.54) ALDH1A1ESR1ESR2CYP3A4MAPK1
SCHEMBL3848016 0.80 ALDH1A1 (0.40) ALDH1A1ESR1ESR2CYP3A4MAPK1
SCHEMBL21763332 0.76 CA1 (0.41) ALDH1A1MAPK1CA1CA2CA5A
SCHEMBL14703697 0.76 CA1 (0.41) ALDH1A1MAPK1CA1CA2CA5A
SCHEMBL26120875 0.76 ALDH1A1 (0.48) ALDH1A1ESR1ESR2CYP3A4MAPK1
SCHEMBL292047 0.75 ALDH1A1 (0.50) ALDH1A1MAPK1CA1CA2CA5A
SCHEMBL5080120 0.75 ALDH1A1 (0.43) ALDH1A1MAPK1CA1CA2CA5A
SCHEMBL9275642 0.75 ALDH1A1 (0.43) ALDH1A1MAPK1CA1CA2CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4200310-B1 SPIRO-CYCLOMETALATED IRIDIUM EMITTERS FOR OLED APPLICATIONS UNIV HONG KONG (CN) 2025-11-05 EP disclosed
US-12048245-B2 Compound, organic light-emitting element including the same, display panel and display device WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2024-07-23 US disclosed
US-12048245-B2 Compound, organic light-emitting element including the same, display panel and display device WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2024-07-23 US disclosed
US-12048245-B2 Compound, organic light-emitting element including the same, display panel and display device WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2024-07-23 US disclosed
US-20230357294-A1 SPIRO-CYCLOMETALATED IRIDIUM EMITTERS FOR OLED APPLICATIONS THE UNIVERSITY OF HONG KONG (HK) 2023-11-09 US disclosed
US-20230357294-A1 SPIRO-CYCLOMETALATED IRIDIUM EMITTERS FOR OLED APPLICATIONS THE UNIVERSITY OF HONG KONG (HK) 2023-11-09 US disclosed
CN-116157490-A Spiro metallized iridium emitters for OLED applications 香港大学 2023-05-23 CN disclosed
CN-111675718-B Compound, organic light-emitting device comprising compound, display panel and display device 武汉天马微电子有限公司 2021-12-21 CN disclosed
US-20200403161-A1 COMPOUND, ORGANIC LIGHT-EMITTING ELEMENT INCLUDING THE SAME, DISPLAY PANEL AND DISPLAY DEVICE WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2020-12-24 US disclosed
US-20200403161-A1 COMPOUND, ORGANIC LIGHT-EMITTING ELEMENT INCLUDING THE SAME, DISPLAY PANEL AND DISPLAY DEVICE WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2020-12-24 US disclosed
EP-1999226-B1 NEW MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2015-08-12 EP disclosed
US-8999521-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2015-04-07 US disclosed
US-20140183422-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2014-07-03 US disclosed
US-20140183422-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2014-07-03 US disclosed
US-20140183422-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2014-07-03 US disclosed
EP-2742054-A1 METAL COMPLEXES Merck Patent GmbH (DE) 2014-06-18 EP disclosed
WO-2013020631-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2013-02-14 WO disclosed
US-20090146139-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2009-06-11 US disclosed
EP-1999226-A1 NEW MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES Merck Patent GmbH (DE) 2008-12-10 EP disclosed
WO-2007110129-A1 NEW MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2007-10-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357294-A1 SPIRO-CYCLOMETALATED IRIDIUM EMITTERS FOR OLED APPLICATIONS TALDO1, SRD5A1, SRD5A2 ALDH1A1 191/4885ESR1 2842/4885ESR2 1160/4885
US-20200403161-A1 COMPOUND, ORGANIC LIGHT-EMITTING ELEMENT INCLUDING THE SAME, DISPLAY PANEL AND DISPLAY DEVICE TRMT1L, TLK1, TSPO ALDH1A1 1272/4885ESR1 18/4885ESR2 259/4885
US-12048245-B2 Compound, organic light-emitting element including the same, display panel and display device TRMT1L, TLK1, TSPO ALDH1A1 1272/4885ESR1 18/4885ESR2 259/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.