SCHEMBL426346

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL428542	0.87	AURKA (0.46)	AURKACCNA2CDK2TTKAURKB
	SCHEMBL425165	0.85	MCHR1 (0.47)	AURKACCNA2CDK2TTKAURKB
	SCHEMBL14412450	0.83	AURKA (0.43)	AURKACCNA2CDK2TTKAURKB
	SCHEMBL430604	0.83	AIMP2 (0.47)	AURKACCNA2CDK2TTKAURKB
	SCHEMBL425961	0.82	AIMP2 (0.50)	AURKACCNA2CDK2TTKAURKB
	SCHEMBL425682	0.82	LTA4H (0.50)	LTA4HPDGFRBPDGFRAFGFR1KDR
	SCHEMBL426452	0.81	AIMP2 (0.45)	AURKACCNA2CDK2TTKAURKB
	SCHEMBL14262741	0.78	PRKCQ (0.53)	AURKACCNA2CDK2TTKAURKB
	SCHEMBL429008	0.75	HSD17B10 (0.40)	AURKAAURKBKDRPIK3CA
	SCHEMBL14131870	0.75	MAPT (0.50)	KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.