Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY2A | P04746 | 9/20 | 0.62 |
| ▸ | AMY1A | P0DUB6 | 3/20 | 0.57 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.51 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.51 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.51 |
| ▸ | ENGASE | Q8NFI3 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | MGAM | O43451 | 2/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | CD209 | Q9NNX6 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27235 | 1.00 | AMY2A (0.62) | AMY2AAMY1ALGALS8LGALS3LGALS4 | |
| SCHEMBL10702505 | 1.00 | AMY2A (0.62) | AMY2AAMY1ALGALS8LGALS3LGALS4 | |
| SCHEMBL20169497 | 0.92 | AMY2A (0.55) | AMY2AAMY1ALGALS8LGALS3LGALS4 | |
| SCHEMBL24495313 | 0.92 | LGALS8 (0.56) | AMY2AAMY1ALGALS8LGALS3LGALS4 | |
| SCHEMBL12648833 | 0.92 | LGALS8 (0.56) | AMY2AAMY1ALGALS8LGALS3LGALS4 | |
| SCHEMBL12595483 | 0.92 | LGALS8 (0.56) | AMY2AAMY1ALGALS8LGALS3LGALS4 | |
| SCHEMBL16510207 | 0.92 | LGALS8 (0.56) | AMY2AAMY1ALGALS8LGALS3LGALS4 | |
| SCHEMBL16506646 | 0.92 | LGALS8 (0.56) | AMY2AAMY1ALGALS8LGALS3LGALS4 | |
| SCHEMBL12595429 | 0.92 | LGALS8 (0.56) | AMY2AAMY1ALGALS8LGALS3LGALS4 | |
| SCHEMBL21243215 | 0.91 | LGALS3 (0.60) | AMY2ALGALS8LGALS3LGALS4ENGASE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090047272-A1 | Compositions with Modified Nucleases Targeted to Viral Nucleic Acids and Methods of Use for Prevention and Treatment of Viral Diseases | NANONASE, INC. | 2009-02-19 | — | — | US | claimed |
| EP-1734991-A2 | COMPOSITIONS WITH MODIFIED NUCLEASES TARGETED TO VIRAL NUCLEIC ACIDS AND METHODS OF USE FOR PREVENTION AND TREATMENT OF VIRAL DISEASES | Avirid, Inc. (US) | 2006-12-27 | — | — | EP | claimed |
| WO-2005115444-A2 | COMPOSITIONS WITH MODIFIED NUCLEASES TARGETED TO VIRAL NUCLEIC ACIDS AND METHODS OF USE FOR PREVENTION AND TREATMENT OF VIRAL DISEASES | AVIRID, INC. (US) | 2005-12-08 | — | — | WO | claimed |
| US-10335372-B2 | Compositions with modified nucleases targeted to viral nucleic acids and methods of use for prevention and treatment of viral diseases | Appelbaum, Jacob G. (US) | 2019-07-02 | — | — | US | disclosed |
| US-20170209376-A1 | COMPOSITIONS WITH MODIFIED NUCLEASES TARGETED TO VIRAL NUCLEIC ACIDS AND METHODS OF USE FOR PREVENTION AND TREATMENT OF VIRAL DISEASES | NANONASE, INC. | 2017-07-27 | — | — | US | disclosed |
| US-9592277-B2 | Compositions with modified nucleases targeted to viral nucleic acids and methods of use for prevention and treatment of viral diseases | AVIRID, INC. (US) | 2017-03-14 | — | — | US | disclosed |
| US-20090047272-A1 | Compositions with Modified Nucleases Targeted to Viral Nucleic Acids and Methods of Use for Prevention and Treatment of Viral Diseases | NANONASE, INC. | 2009-02-19 | — | — | US | disclosed |
| EP-1734991-A2 | COMPOSITIONS WITH MODIFIED NUCLEASES TARGETED TO VIRAL NUCLEIC ACIDS AND METHODS OF USE FOR PREVENTION AND TREATMENT OF VIRAL DISEASES | Avirid, Inc. (US) | 2006-12-27 | — | — | EP | disclosed |
| WO-2005115444-A2 | COMPOSITIONS WITH MODIFIED NUCLEASES TARGETED TO VIRAL NUCLEIC ACIDS AND METHODS OF USE FOR PREVENTION AND TREATMENT OF VIRAL DISEASES | AVIRID, INC. (US) | 2005-12-08 | — | — | WO | disclosed |
| US-4927753-A | FUCOSE DEHYDROGENASE | TAKARA SHUZO CO., LTD. (JP) | 1990-05-22 | — | — | US | disclosed |