SCHEMBL4264702

SCHEMBL4264702

CCc1c(O)nc2ccccc2c1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.47
ALDH1A1 P00352 2/20 0.47
HPGD P15428 2/20 0.47
GAA P10253 1/20 0.47
MAPT P10636 2/20 0.45
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
RXFP1 Q9HBX9 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
TNKS2 Q9H2K2 1/20 0.41
CYP1A2 P05177 1/20 0.41
POLB P06746 1/20 0.41
RAD52 P43351 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ERN1 O75460 1/20 0.40
GLA P06280 1/20 0.39
LMNA P02545 2/20 0.38
TLR7 Q9NYK1 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
GPR3 P46089 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14533471 0.87 KDM4E (0.53) KDM4EALDH1A1HPGDGAAMAPT
SCHEMBL27999716 0.84 POLB (0.50) KDM4EALDH1A1HPGDGAAMAPT
SCHEMBL6818967 0.84 GPR3 (0.50) KDM4EALDH1A1HPGDGAAMEN1
SCHEMBL10647975 0.82 TLR8 (0.52) KDM4EALDH1A1HPGDGAAMAPT
SCHEMBL2809797 0.80 ALDH1A1 (0.52) KDM4EALDH1A1HPGDGAAMAPT
SCHEMBL28457049 0.80 PDE10A (0.53) MAPTMEN1KMT2ATNKS2POLB
SCHEMBL14533531 0.80 GCGR (0.43) KDM4EALDH1A1HPGDGAAMAPT
SCHEMBL14625667 0.80 KDM4E (0.46) KDM4EALDH1A1HPGDGAAMAPT
SCHEMBL11775553 0.79 KDM4E (0.51) KDM4EALDH1A1HPGDGAAMAPT
SCHEMBL14967518 0.77 MAPT (0.40) KDM4EALDH1A1HPGDGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7605215-B2 Process for producing olefin copolymerization catalyst and process for producing olefin copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-20 US disclosed
US-20080227937-A1 Process for Producing Olefin Copolymerization Catalyst and Process for Producing Olefin Copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-18 US disclosed