SCHEMBL426471

SCHEMBL426471

Cc1ccc2c(C(=O)O)c(O)c(O)c(C(C)C)c2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LDHA P00338 12/20 1.00
LDHB P07195 11/20 1.00
ALB P02768 6/20 1.00
DHODH Q02127 2/20 0.44
CSNK2A1 P68400 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29750641 1.00 LDHA (1.00) LDHALDHBALBDHODHCSNK2A1
SCHEMBL19202488 0.83 LDHA (0.77) LDHALDHBALBDHODHCSNK2A1
SCHEMBL7181495 0.81 LDHA (1.00) LDHALDHBALBDHODHCSNK2A1
SCHEMBL7173943 0.81 LDHA (1.00) LDHALDHBALB
SCHEMBL26027710 0.80 LDHA (0.66) LDHALDHBALBDHODH
SCHEMBL19202493 0.80 LDHA (0.72) LDHALDHBALBDHODHCSNK2A1
SCHEMBL8460263 0.79 LDHA (0.65) LDHALDHBALB
SCHEMBL29555202 0.77 ALB (1.00) LDHALDHBALB
SCHEMBL2622271 0.77 ALB (1.00) LDHALDHBALB
SCHEMBL8459960 0.76 ALB (1.00) LDHALDHBALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8690857-B2 Alleviate back pain with lactic acid inhibitors ALEEVA MEDICAL INC. (US) 2014-04-08 US claimed
US-20120022425-A1 Alleviate back pain with lactic acid inhibitors YEUNG JEFFREY ERIC (US) 2012-01-26 US claimed
EP-4683579-A1 RELIEVE BACK PAIN AND/OR REBUILDING INTERVERTERAL DISC Yeung, Jeffrey E. (US) 2026-01-28 EP disclosed
WO-2024158529-A1 RELIEVE BACK PAIN AND/OR REBUILDING INTERVERTERAL DISC YEUNG JEFFREY E (US) 2024-08-02 WO disclosed
US-10561503-B2 Method for relieving pain and regenerating intervertebral disc ALEEVA MEDICAL INC. (US) 2020-02-18 US disclosed
US-10292827-B2 Method for relieving back/neck pain and repairing intervertebral disc ALLEVA MEDICAL INC. 2019-05-21 US disclosed
US-20180207004-A1 Method for relieving pain and regenerating intervertebral disc YEUNG JEFFREY E (US) 2018-07-26 US disclosed
US-9980821-B2 Method for relieving pain and regenerating intervertebral disc ALEEVA MEDICAL INC. (US) 2018-05-29 US disclosed
EP-2688499-B1 TISSUE REPAIR WITH SPACE-SEEKING SPIRALS OF FILAMENT YEUNG JEFFREY E (US) 2017-09-27 EP disclosed
US-20160193054-A1 Method of tissue repair with spiral of filament YEUNG JEFFREY E (US) 2016-07-07 US disclosed
US-9326791-B2 Tissue repair with space-seeking spirals of filament ALEEVA MEDICAL INC. (US) 2016-05-03 US disclosed
EP-2688499-A1 TISSUE REPAIR WITH SPACE-SEEKING SPIRALS OF FILAMENT Yeung, Jeffrey E. (US) 2014-01-29 EP disclosed
US-20130289599-A1 TISSUE REPAIR WITH SPACE-SEEKING SPIRALS OF FILAMENT YEUNG JEFFREY ERIC (US) 2013-10-31 US disclosed
US-8449490-B2 Disc shunt delivery with stepped needle ALEEVA MEDICAL INC. (US) 2013-05-28 US disclosed
WO-2012128829-A1 TISSUE REPAIR WITH SPACE-SEEKING SPIRALS OF FILAMENT YEUNG JEFFREY E (US) 2012-09-27 WO disclosed
US-20120065570-A1 Disc shunt delivery with stepped needle YEUNG JEFFREY E (US) 2012-03-15 US disclosed
US-20120022425-A1 Alleviate back pain with lactic acid inhibitors YEUNG JEFFREY ERIC (US) 2012-01-26 US disclosed
CN-1670200-A Lactate dehydrogenase of clonorchis sinensis, its coding nucleic acid and application UNIV SUN YAT SEN (CN) 2005-09-21 CN disclosed
US-5936120-A FOR TREATING HUMAN IMMMUNODEFICIENCY VIRUS INFECTION IN MAMMALS UNIVERSITY OF NEW MEXICO (US) 1999-08-10 US disclosed
US-5780675-A NONCYTOTOXIC; SAPONIFICATION, CYCLIZATION, REDUCTION, REHYDRATION; CATALYTIC HYDROGENOLYSIS THE UNIVERSITY OF NEW MEXICO (US) 1998-07-14 US disclosed