SCHEMBL4265950

SCHEMBL4265950

CN(C)c1cc(N(C)C)nc(N(C)C)n1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.56
CYP1A2 P05177 1/20 0.56
THRB P10828 1/20 0.56
BLM P54132 1/20 0.56
CREBBP Q92793 1/20 0.56
HSD17B10 Q99714 1/20 0.56
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
MAPT P10636 4/20 0.43
APAF1 O14727 4/20 0.43
NSD2 O96028 3/20 0.43
SAE1 Q9UBE0 3/20 0.43
UBA2 Q9UBT2 3/20 0.43
SENP8 Q96LD8 3/20 0.43
SENP7 Q9BQF6 3/20 0.43
SENP6 Q9GZR1 3/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
CASP3 P42574 1/20 0.43
KDM4E B2RXH2 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13780086 0.85 MEN1 (0.59) LMNACYP1A2THRBBLMCREBBP
SCHEMBL9270907 0.83 LMNA (0.43) LMNACYP1A2THRBBLMCREBBP
SCHEMBL2789514 0.83 KMT2A (0.47) LMNACYP1A2THRBBLMCREBBP
SCHEMBL10375772 0.83 LMNA (0.43) LMNACYP1A2THRBBLMCREBBP
SCHEMBL11701255 0.79 MAPT (0.42) LMNACYP1A2THRBBLMCREBBP
SCHEMBL14087376 0.79 DYRK1A (0.41) LMNACYP1A2THRBBLMCREBBP
SCHEMBL13990723 0.79 HRH4 (0.50) LMNACYP1A2THRBBLMCREBBP
SCHEMBL13990859 0.79 LMNA (0.40) LMNACYP1A2THRBBLMCREBBP
SCHEMBL3404588 0.76 CTSA (0.46) LMNACYP1A2THRBBLMCREBBP
SCHEMBL13692143 0.76 CTSA (0.43) LMNACYP1A2THRBBLMCREBBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7605215-B2 Process for producing olefin copolymerization catalyst and process for producing olefin copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-20 US disclosed
US-20080227937-A1 Process for Producing Olefin Copolymerization Catalyst and Process for Producing Olefin Copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-18 US disclosed