Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | APAF1 | O14727 | 4/20 | 0.38 |
| ▸ | NSD2 | O96028 | 3/20 | 0.38 |
| ▸ | SAE1 | Q9UBE0 | 3/20 | 0.38 |
| ▸ | UBA2 | Q9UBT2 | 3/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10377966 | 0.85 | LMNA (0.53) | LMNACYP1A2THRBBLMCREBBP | |
| SCHEMBL4265950 | 0.83 | LMNA (0.56) | LMNACYP1A2THRBBLMCREBBP | |
| SCHEMBL11481158 | 0.77 | NOS3 (0.48) | LMNACYP1A2THRBBLMCREBBP | |
| SCHEMBL4256097 | 0.77 | NUDT1 (0.42) | NUDT1KMT2AMEN1TSHRNOS3 | |
| SCHEMBL2467611 | 0.76 | LMNA (0.42) | LMNACYP1A2THRBBLMCREBBP | |
| SCHEMBL11398865 | 0.76 | LMNA (0.42) | LMNACYP1A2THRBBLMCREBBP | |
| SCHEMBL13780086 | 0.74 | MEN1 (0.59) | LMNACYP1A2THRBBLMCREBBP | |
| SCHEMBL9270907 | 0.73 | LMNA (0.43) | LMNACYP1A2THRBBLMCREBBP | |
| SCHEMBL2789514 | 0.73 | KMT2A (0.47) | LMNACYP1A2THRBBLMCREBBP | |
| SCHEMBL9380659 | 0.72 | LMNA (0.44) | LMNACYP1A2THRBBLMCREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59200253-A | — | — | None | — | — | JP | disclosed |
| EP-0189045-B1 | PYRIDOPYRIMIDINES, DIFFERENT PROCESSES FOR THEIR PREPARATION AS WELL AS THEIR USE AS MEDICAMENTS | BAYER AG (DE) | 1990-02-14 | — | — | EP | disclosed |
| US-4621082-A | Pyridopyrimidines, pharmaceutical compositions and use | BAYER AKTIENGESELLSCHAFT (DE) | 1986-11-04 | — | — | US | disclosed |
| EP-0189045-A2 | Pyridopyrimidines, different processes for their preparation as well as their use as medicaments | BAYER AG (DE) | 1986-07-30 | — | — | EP | disclosed |
| JP-S59200253-A | POSITIVE ELECTROSTATIC CHEARGEABLE TONER FOR TWO- COMPONENT DEVELOPER | FUJITSU LTD | 1984-11-13 | — | — | JP | disclosed |
| US-4331805-A | OPTICAL BRIGHTENERS | CIBA-GEIGY CORPORATION (US) | 1982-05-25 | — | — | US | disclosed |
| US-4236003-A | OPTICAL BRIGHTENERS | CIBA-GEIGY CORPORATION (US) | 1980-11-25 | — | — | US | disclosed |
| US-4157443-A | OPTICAL BRIGHTENERS | CIBA-GEIGY CORPORATION (US) | 1979-06-05 | — | — | US | disclosed |