Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | APAF1 | O14727 | 3/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | NSD2 | O96028 | 3/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 3/20 | 0.40 |
| ▸ | UBA2 | Q9UBT2 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12888669 | 0.87 | L3MBTL1 (0.48) | MAPTLMNAKDM4EL3MBTL1CYP1A2 | |
| SCHEMBL4265950 | 0.79 | LMNA (0.56) | MAPTLMNAAPAF1SENP8SENP7 | |
| SCHEMBL2238434 | 0.79 | SMN1; SMN2 (0.49) | MAPTLMNAKDM4EL3MBTL1CYP1A2 | |
| SCHEMBL10739183 | 0.79 | LMNA (0.47) | MAPTLMNASENP8SENP7SENP6 | |
| SCHEMBL12051584 | 0.79 | PDE2A (0.48) | LMNAKDM4EL3MBTL1CYP1A2KMT2A | |
| SCHEMBL11728658 | 0.78 | L3MBTL1 (0.40) | MAPTLMNAKDM4EL3MBTL1CYP1A2 | |
| SCHEMBL1671075 | 0.78 | SMN1; SMN2 (0.41) | MAPTLMNAKDM4EL3MBTL1CYP1A2 | |
| SCHEMBL9380659 | 0.78 | LMNA (0.44) | MAPTLMNAKDM4EL3MBTL1CYP1A2 | |
| SCHEMBL1576997 | 0.78 | NUDT1 (0.52) | LMNAKDM4EL3MBTL1KMT2AGLA | |
| SCHEMBL14225685 | 0.78 | KMT2A (0.57) | LMNAKDM4EL3MBTL1CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4046503-A | DEVELOPER-COUPLER HAIR DYES BASED ON ALKOXY-TRIAMINO-PYRIMIDINES | HENKEL & CIE GMBH (DT) | 1977-09-06 | — | — | US | claimed |