Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.42 |
| ▸ | ACE | P12821 | 3/20 | 0.42 |
| ▸ | CPA1 | P15085 | 3/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 6/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4271239 | 0.90 | ITGB1 (0.41) | MMEACECPA1ACE2ITGB1 | |
| SCHEMBL4264235 | 0.82 | MME (0.41) | MMECPA1 | |
| SCHEMBL4266200 | 0.73 | MME (0.40) | MMEACECPA1ACE2ITGB1 | |
| SCHEMBL5727492 | 0.67 | KMT2A (0.33) | KMT2AALDH1A1MEN1 | |
| SCHEMBL27630173 | 0.67 | ITGA4 (0.45) | MMEACECPA1ACE2ITGB1 | |
| SCHEMBL16294576 | 0.66 | ITGB1 (0.60) | MMEITGB1ITGA4ALDH1A1 | |
| SCHEMBL4266433 | 0.64 | PTPN1 (0.53) | MMEACECPA1ACE2ITGB1 | |
| SCHEMBL5404050 | 0.63 | ITGB3 (0.53) | ITGA4ALDH1A1 | |
| SCHEMBL18180178 | 0.62 | NAALAD2 (0.78) | MMEKMT2AALDH1A1MEN1 | |
| SCHEMBL19969196 | 0.62 | NAALAD2 (0.78) | MMEKMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090082392-A1 | Substituted Carboxylic Acids | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY LLC | 2009-03-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090082392-A1 | Substituted Carboxylic Acids | PTPRJ, PTPRS, PTPRG | MME 3001/4885ACE 1279/4885CPA1 1736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.