SCHEMBL4264235

SCHEMBL4264235

O=C(O)C(CC(=O)C1(n2ccc3ccccc32)C=CC(c2ccccc2)=CC1)Cc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MME P08473 10/20 0.41
CPA1 P15085 6/20 0.39
CPA3 P15088 2/20 0.39
CPB1 P15086 1/20 0.39
CPB2 Q96IY4 1/20 0.39
CYP1A2 P05177 1/20 0.36
FOLH1 Q04609 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4266201 0.82 MME (0.42) MMECPA1
SCHEMBL4264232 0.72 CPA1 (0.40) MMECPA1CPA3CPB1CPB2
SCHEMBL5727492 0.67 KMT2A (0.33)
SCHEMBL5768014 0.66 PTPN1 (0.40) MMECPA1CPA3CPB1CPB2
SCHEMBL4267863 0.63 KMO (0.48) MMECPA1CPA3CPB1CPB2
SCHEMBL5688996 0.60 CPA1 (1.00) MMECPA1CPA3CPB1CPB2
SCHEMBL1915564 0.60 CPA1 (1.00) MMECPA1CPA3CPB1CPB2
SCHEMBL393002 0.60 CPA1 (1.00) MMECPA1CPA3CPB1CPB2
SCHEMBL4664822 0.59 CYP1A2 (1.00) MMECPA1CPA3CPB1CPB2
SCHEMBL3421012 0.59 CPA1 (0.96) MMECPA1CPA3CPB1CPB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090082392-A1 Substituted Carboxylic Acids THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY LLC 2009-03-26 US claimed
JP-2006525329-A 2006-11-09 JP claimed
EP-1620420-A2 SUBSTITUTED CARBOXYLIC ACIDS The Institutes for Pharmaceutical Discovery, LLC (US) 2006-02-01 EP claimed
WO-2004099168-A2 SUBSTITUTED CARBOXYLIC ACIDS THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, LLC (US) 2004-11-18 WO claimed
EP-1620420-A2 SUBSTITUTED CARBOXYLIC ACIDS The Institutes for Pharmaceutical Discovery, LLC (US) 2006-02-01 EP disclosed
WO-2004099168-A2 SUBSTITUTED CARBOXYLIC ACIDS THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, LLC (US) 2004-11-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090082392-A1 Substituted Carboxylic Acids PTPRJ, PTPRS, PTPRG MME 3001/4885CPA1 1736/4885CPA3 3626/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.