SCHEMBL4266296

SCHEMBL4266296

O=C(O)CN1CCN(CC(=O)O)CCN2CCN(CC1)CC(=O)OC(=O)C2

nearest known ligand 0.56

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.46
SLC6A9 P48067 1/20 0.37
TGM2 P21980 2/20 0.35
S1PR1 P21453 1/20 0.33
EGLN1 Q9GZT9 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL529016 0.82 HSD17B10 (0.43) HSD17B10TSHR
SCHEMBL24090588 0.78 HSD17B10 (0.41) HSD17B10SLC6A9TGM2S1PR1TSHR
SCHEMBL1468774 0.77 HSD17B10 (0.56) HSD17B10SLC6A9TGM2S1PR1
SCHEMBL9116656 0.77 HSD17B10 (0.56) HSD17B10SLC6A9TGM2S1PR1
SCHEMBL9119179 0.77 HSD17B10 (0.56) HSD17B10SLC6A9TGM2S1PR1
SCHEMBL9119800 0.75 HSD17B10 (0.54) HSD17B10SLC6A9TGM2S1PR1
SCHEMBL9117714 0.75 HSD17B10 (0.54) HSD17B10SLC6A9TGM2S1PR1
SCHEMBL9118000 0.75 HSD17B10 (0.54) HSD17B10SLC6A9TGM2S1PR1
SCHEMBL25629531 0.75 HSD17B10 (0.34) HSD17B10
SCHEMBL173508 0.74 HSD17B10 (0.64) HSD17B10SLC6A9S1PR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7605146-B2 Process for producing an amide compound NIHON MEDI-PHYSICS COMPANY, LIMITED (JP) 2009-10-20 US claimed
EP-1199312-B1 Process for producing an amide compound SUMITOMO CHEMICAL CO (JP) 2004-07-21 EP claimed
US-20020077456-A1 Process for producing an amide compound NIHON MEDI-PHYSICS COMPANY, LIMITED (JP) 2002-06-20 US claimed
EP-1199312-A2 Process for producing an amide compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-04-24 EP claimed
US-7605146-B2 Process for producing an amide compound NIHON MEDI-PHYSICS COMPANY, LIMITED (JP) 2009-10-20 US disclosed
EP-1199312-B1 Process for producing an amide compound SUMITOMO CHEMICAL CO (JP) 2004-07-21 EP disclosed
US-20020077456-A1 Process for producing an amide compound NIHON MEDI-PHYSICS COMPANY, LIMITED (JP) 2002-06-20 US disclosed
EP-1199312-A2 Process for producing an amide compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-04-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020077456-A1 Process for producing an amide compound NAAA, ACMSD, CPS1 HSD17B10 1556/4885SLC6A9 2241/4885TGM2 736/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.