Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28832024 | 0.96 | ALDH1A1 (0.30) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2121676 | 0.96 | ALDH1A1 (0.30) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2829435 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL449285 | 0.92 | ALDH1A1 (0.31) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2957044 | 0.92 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL190432 | 0.92 | ALDH1A1 (0.36) | ALDH1A1 | |
| Iodide SCHEMBL2828204 | 0.89 | ALDH1A1 (0.30) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL320093 | 0.89 | ALDH1A1 (0.30) | ALDH1A1 | |
| Bromide SCHEMBL2832239 | 0.89 | ALDH1A1 (0.30) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL30804601 | 0.89 | ALDH1A1 (0.30) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10300473-B2 | Catalytic composition comprising nickel and a ligand of the phosphane complexed with nickel type, and use thereof in a olefin oligomerisation method | IFP Energies Nouvelles (FR) | 2019-05-28 | — | — | US | claimed |
| US-20180221861-A1 | NOVEL CATALYTIC COMPOSITION COMPRISING NICKEL AND A LIGAND OF THE PHOSPHANE COMPLEXED WITH NICKEL TYPE, AND USE THEREOF IN A OLEFIN OLIGOMERISATION METHOD | IFP Energies Nouvelles (FR) | 2018-08-09 | — | — | US | claimed |
| US-10300473-B2 | Catalytic composition comprising nickel and a ligand of the phosphane complexed with nickel type, and use thereof in a olefin oligomerisation method | IFP Energies Nouvelles (FR) | 2019-05-28 | — | — | US | disclosed |
| US-20180221861-A1 | NOVEL CATALYTIC COMPOSITION COMPRISING NICKEL AND A LIGAND OF THE PHOSPHANE COMPLEXED WITH NICKEL TYPE, AND USE THEREOF IN A OLEFIN OLIGOMERISATION METHOD | IFP Energies Nouvelles (FR) | 2018-08-09 | — | — | US | disclosed |
| US-7482412-B2 | Process for manufacturing cycloolefin addition polymer | JSR CORPORATION (JP) | 2009-01-27 | — | — | US | disclosed |
| US-20080085979-A1 | PROCESS FOR MANUFACTURING CYCLOOLEFIN ADDITION POLYMER | JSR CORPORATION (JP) | 2008-04-10 | — | — | US | disclosed |