Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4506407 | 0.96 | ALDH1A1 (0.30) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL320093 | 0.96 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL31528332 | 0.92 | ALDH1A1 (0.32) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2957044 | 0.92 | ALDH1A1 (0.31) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4266973 | 0.92 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL190432 | 0.92 | ALDH1A1 (0.36) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2121675 | 0.89 | ALDH1A1 (0.30) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2121676 | 0.89 | ALDH1A1 (0.30) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28832024 | 0.89 | ALDH1A1 (0.30) | ALDH1A1 | |
| Bromide SCHEMBL29564533 | 0.89 | ALDH1A1 (0.30) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567482-B1 | PROCESS FOR THE PREPARATION OF PHENYLMALONIC ACID DINITRILES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-02-17 | — | — | EP | claimed |
| US-20060135805-A1 | Process for the preparation of phenylmalonic acid dinitriles | SYNGENTA CROP PROTECTION, INC. | 2006-06-22 | — | — | US | claimed |
| EP-2155645-B1 | HERBICIDALLY ACTIVE BICYCLIC 1,3-DIONE COMPOUNDS | SYNGENTA LTD (GB) | 2017-06-14 | — | — | EP | disclosed |
| EP-2173755-B1 | NOVEL HERBICIDES | SYNGENTA LTD (GB) | 2017-05-17 | — | — | EP | disclosed |
| EP-2459547-B1 | HERBICIDALLY ACTIVE HETEROARYL-SUBSTITUTED CYCLIC DIONES OR DERIVATIVES THEREOF | SYNGENTA LTD (GB) | 2016-04-20 | — | — | EP | disclosed |
| EP-2997824-A1 | NOVEL HERBICIDES | Syngenta Participations AG. (CH) | 2016-03-23 | — | — | EP | disclosed |
| EP-2375898-B1 | NOVEL HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-09-16 | — | — | EP | disclosed |
| EP-2313370-B1 | 5-HETEROCYCLYLALKYL-3-HYDROXY-2-PHENYLCYCLOPENT-2-ENONES AS HERBICIDES | SYNGENTA LTD (GB) | 2015-08-19 | — | — | EP | disclosed |
| US-9096560-B2 | 5-heterocyclylalkyl-3-hydroxy-2-phenylcyclopent-2-enones as herbicides | SYNGENTA LIMITED (GB) | 2015-08-04 | — | — | US | disclosed |
| US-9051300-B2 | Herbicides | SYNGENTA LIMITED (GB) | 2015-06-09 | — | — | US | disclosed |
| US-9006429-B2 | Herbicidal pyrandione, thiopyrandione, and cyclohexanetrione derivatives | SYNGENTA CROP PROTECTION, LLC (US) | 2015-04-14 | — | — | US | disclosed |
| US-20080085979-A1 | PROCESS FOR MANUFACTURING CYCLOOLEFIN ADDITION POLYMER | JSR CORPORATION (JP) | 2008-04-10 | — | — | US | disclosed |
| US-7268247-B2 | Process for the preparation of phenylmalonic acid dinitriles | SYNGENTA CROP PROTECTION, INC. (US) | 2007-09-11 | — | — | US | disclosed |
| US-20060135805-A1 | Process for the preparation of phenylmalonic acid dinitriles | SYNGENTA CROP PROTECTION, INC. | 2006-06-22 | — | — | US | disclosed |
| EP-1481970-B1 | Novel herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2006-03-22 | — | — | EP | disclosed |
| US-20050187110-A1 | mixtures with plant safening agents used for selectively controlling weeds and grasses in crops of useful plants | MAETZKE THOMAS (CH) | 2005-08-25 | — | — | US | disclosed |
| US-20050164883-A1 | agronomically tolerable salts, isomers and enantiomers of those compounds, are suitable for use as herbicides | MAETZKE THOMAS (CH) | 2005-07-28 | — | — | US | disclosed |
| US-6894005-B1 | Heterocyclic compound containing phenyl groups; postemergence herbicides | SYNGENTA CROP PROTECTION, INC. (US) | 2005-05-17 | — | — | US | disclosed |
| EP-1481970-A1 | Novel herbicides | Syngenta Participations AG (CH) | 2004-12-01 | — | — | EP | disclosed |
| EP-1210333-B1 | p-Tolyl-heterocycles as herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2004-11-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050164883-A1 | agronomically tolerable salts, isomers and enantiomers of those compounds, are suitable for use as herbicides | DDT, SULT2A1, GSTA1 | ALDH1A1 65/4885 |
| US-20060135805-A1 | Process for the preparation of phenylmalonic acid dinitriles | ME1, PDK2, PDK4 | ALDH1A1 841/4885 |
| US-20050187110-A1 | mixtures with plant safening agents used for selectively controlling weeds and grasses in crops of useful plants | PIN1, GMDS, DDT | ALDH1A1 345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.