Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | NR1I3 | Q14994 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 4/20 | 0.34 |
| ▸ | FLT1 | P17948 | 3/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.33 |
| ▸ | CLK2 | P49760 | 4/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.33 |
| ▸ | CLK1 | P49759 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3056848 | 0.82 | KDR (0.43) | ALDH1A1LMNAMAPTKDRFLT1 | |
| Ammonia Solution, Strong SCHEMBL4262504 | 0.78 | KDM4E (0.39) | NR1H4KDM4EMAPTCLK4ROCK2 | |
| Ammonia Solution, Strong SCHEMBL4265881 | 0.72 | POLB (0.31) | NR1H4KDM4ECLK4CLK2DYRK1A | |
| Ammonia Solution, Strong SCHEMBL4268221 | 0.70 | LMNA (0.51) | NR1H4ALDH1A1ALOX15LMNAMAPT | |
| Ammonia Solution, Strong SCHEMBL4262055 | 0.68 | LMNA (0.36) | NR1H4ALOX15LMNAMAPTMAPK1 | |
| Ammonia Solution, Strong SCHEMBL4275960 | 0.67 | MAPT (0.46) | ALDH1A1LMNAMAPTKDR | |
| SCHEMBL18768854 | 0.67 | CYP1A2 (0.57) | CYP3A4LMNAMAPTCLK4CLK2 | |
| SCHEMBL2854484 | 0.65 | CYP1A2 (0.68) | TAAR1NR1I3KDM4EALDH1A1CYP3A4 | |
| SCHEMBL29444840 | 0.63 | MEN1 (0.56) | TAAR1KDM4EALDH1A1CYP3A4GLA | |
| SCHEMBL3056838 | 0.62 | MAPT (0.41) | KDM4EALDH1A1MAPTKDRFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090131445-A1 | Furazano '3, 4-B! Pyrazines and Their Use as Anti-Tumor Agents | COMPASS PHARMACEUTICALS LLC (US) | 2009-05-21 | — | — | US | claimed |
| US-20090131445-A1 | Furazano '3, 4-B! Pyrazines and Their Use as Anti-Tumor Agents | COMPASS PHARMACEUTICALS LLC (US) | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131445-A1 | Furazano '3, 4-B! Pyrazines and Their Use as Anti-Tumor Agents | CDC73, RB1, CA5A | HDAC4 1392/4885HDAC1 1162/4885HDAC6 2211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.