Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | GLP1R | P43220 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL4262055 | 0.87 | LMNA (0.36) | LMNAHTTPOLBMAPTTP53 | |
| Ammonia Solution, Strong SCHEMBL4275960 | 0.78 | MAPT (0.46) | LMNAHTTPOLBMAPTTP53 | |
| Ammonia Solution, Strong SCHEMBL4262504 | 0.78 | KDM4E (0.39) | HTTPOLBMAPTTP53MAPK1 | |
| SCHEMBL3052187 | 0.77 | HTT (0.57) | LMNAHTTPOLBMAPTTP53 | |
| Ammonia Solution, Strong SCHEMBL4262241 | 0.71 | GUSB (0.49) | HTTMAPTTP53SMN1; SMN2CCR2 | |
| Ammonia Solution, Strong SCHEMBL4267150 | 0.70 | HDAC4 (0.38) | LMNAMAPTMAPK1NR1H4ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL4265881 | 0.69 | POLB (0.31) | POLBNR1H4 | |
| Ammonia Solution, Strong SCHEMBL4270918 | 0.69 | TUBB4A (0.48) | HTTPOLBMAPTTP53SMN1; SMN2 | |
| SCHEMBL3051396 | 0.66 | TP53 (0.55) | LMNAHTTPOLBMAPTTP53 | |
| Ammonia Solution, Strong SCHEMBL4262270 | 0.66 | MAPT (0.53) | LMNAHTTPOLBMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090131445-A1 | Furazano '3, 4-B! Pyrazines and Their Use as Anti-Tumor Agents | COMPASS PHARMACEUTICALS LLC (US) | 2009-05-21 | — | — | US | claimed |
| US-20090131445-A1 | Furazano '3, 4-B! Pyrazines and Their Use as Anti-Tumor Agents | COMPASS PHARMACEUTICALS LLC (US) | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131445-A1 | Furazano '3, 4-B! Pyrazines and Their Use as Anti-Tumor Agents | CDC73, RB1, CA5A | LMNA 1452/4885HTT 4435/4885POLB 1467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.