⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21835 | 0.76 | MEN1 (0.30) | — | |
| SCHEMBL8742 | 0.72 | — | — | |
| SCHEMBL6536476 | 0.69 | MEN1 (0.31) | — | |
| SCHEMBL6681441 | 0.68 | — | — | |
| SCHEMBL4741585 | 0.64 | ALDH1A1 (0.35) | — | |
| SCHEMBL9662746 | 0.63 | GDA (0.30) | — | |
| SCHEMBL5958156 | 0.61 | ABL1 (0.34) | — | |
| SCHEMBL30900330 | 0.56 | KMT2A (0.39) | — | |
| SCHEMBL18050892 | 0.56 | ALDH1A1 (0.44) | — | |
| SCHEMBL14446948 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115747223-A | Nucleic acid compositions of anti-coronavirus antibodies | 中国人民解放军军事科学院军事医学研究院 | 2023-03-07 | — | — | CN | disclosed |
| US-10335372-B2 | Compositions with modified nucleases targeted to viral nucleic acids and methods of use for prevention and treatment of viral diseases | Appelbaum, Jacob G. (US) | 2019-07-02 | — | — | US | disclosed |
| US-20170209376-A1 | COMPOSITIONS WITH MODIFIED NUCLEASES TARGETED TO VIRAL NUCLEIC ACIDS AND METHODS OF USE FOR PREVENTION AND TREATMENT OF VIRAL DISEASES | NANONASE, INC. | 2017-07-27 | — | — | US | disclosed |
| US-9592277-B2 | Compositions with modified nucleases targeted to viral nucleic acids and methods of use for prevention and treatment of viral diseases | AVIRID, INC. (US) | 2017-03-14 | — | — | US | disclosed |
| US-20090047272-A1 | Compositions with Modified Nucleases Targeted to Viral Nucleic Acids and Methods of Use for Prevention and Treatment of Viral Diseases | NANONASE, INC. | 2009-02-19 | — | — | US | disclosed |
| EP-1734991-A2 | COMPOSITIONS WITH MODIFIED NUCLEASES TARGETED TO VIRAL NUCLEIC ACIDS AND METHODS OF USE FOR PREVENTION AND TREATMENT OF VIRAL DISEASES | Avirid, Inc. (US) | 2006-12-27 | — | — | EP | disclosed |
| WO-2005115444-A2 | COMPOSITIONS WITH MODIFIED NUCLEASES TARGETED TO VIRAL NUCLEIC ACIDS AND METHODS OF USE FOR PREVENTION AND TREATMENT OF VIRAL DISEASES | AVIRID, INC. (US) | 2005-12-08 | — | — | WO | disclosed |