Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL214954 | 0.88 | — | — | |
| SCHEMBL28603365 | 0.83 | — | — | |
| SCHEMBL8541874 | 0.82 | CDK1 (0.32) | — | |
| SCHEMBL21835 | 0.78 | MEN1 (0.30) | MEN1BLMKMT2A | |
| SCHEMBL3305619 | 0.78 | ALDH1A1 (0.31) | — | |
| SCHEMBL28757165 | 0.77 | LMNA (0.30) | — | |
| SCHEMBL8742 | 0.75 | — | — | |
| SCHEMBL6681441 | 0.73 | — | — | |
| SCHEMBL4267183 | 0.69 | — | — | |
| SCHEMBL4741585 | 0.69 | ALDH1A1 (0.35) | BLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998596-A | Inhibition of protein kinase activity by aptameric action of oligonucleotides | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1999-12-07 | — | — | US | claimed |
| US-20040170990-A1 | Intracellular nucleic acid inhibitors of small guanine nucleotide exchange factors | WALDEMAR KOLANUS (DE) | 2004-09-02 | — | — | US | disclosed |
| EP-1290142-A4 | SHORT-ROOT GENE, PROMOTER, AND USES THEREOF | UNIV NEW YORK (US) | 2004-06-16 | — | — | EP | disclosed |
| WO-2003094973-A1 | AGENT AND METHOD FOR TRANSPORTING BIOLOGICALLY ACTIVE MOLECULES IN CELLS | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2003-11-20 | — | — | WO | disclosed |
| EP-1333090-A1 | Prionprotein-specific aptamers | NascaCell GmbH (DE) | 2003-08-06 | — | — | EP | disclosed |
| EP-1290142-A1 | SHORT-ROOT GENE, PROMOTER, AND USES THEREOF | NEW YORK UNIVERSITY (US) | 2003-03-12 | — | — | EP | disclosed |
| WO-2002081686-A2 | NUCLEIC ACIDS BINDING A NEUROPEPTIDE | NASCACELL GMBH (DE) | 2002-10-17 | — | — | WO | disclosed |
| EP-1223216-A1 | Intracellular nucleic acid inhibitors of small guanine-nucleotide-exchange factors | NascaCell GmbH (DE) | 2002-07-17 | — | — | EP | disclosed |
| WO-2002053731-A1 | INTRACELLULAR NUCLEIC ACID INHIBITORS OF SMALL GUANINE NUCLEOTIDE EXCHANGE FACTORS | NASCACELL GMBH (DE) | 2002-07-11 | — | — | WO | disclosed |
| WO-2002026955-A2 | HUMAN PROTEASES AND POLYNUCLEOTIDES ENCODING THE SAME | LEXICON GENETICS INCORPORATED (US) | 2002-04-04 | — | — | WO | disclosed |
| WO-2001090314-A1 | SHORT-ROOT GENE, PROMOTER, AND USES THEREOF | NEW YORK UNIVERSITY (US) | 2001-11-29 | — | — | WO | disclosed |
| US-5998596-A | Inhibition of protein kinase activity by aptameric action of oligonucleotides | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1999-12-07 | — | — | US | disclosed |
| EP-0691968-B1 | ACYCLIC NUCLEOSIDE ANALOGS AND OLIGONUCLEOTIDE SEQUENCES CONTAINING THEM | SANOFI SA (FR) | 1997-07-16 | — | — | EP | disclosed |
| US-5576427-A | COMPOUNDS WHICH REPLACE NUCLEOSIDES IN AN OLIGONUCLEOTIDE TO INHIBIT NUCLEASE DEGRADATION OF OLIGONUCLEOTIDE | STERLING WINTHROP, INC. (US) | 1996-11-19 | — | — | US | disclosed |
| WO-1994022864-A1 | ACYCLIC NUCLEOSIDE ANALOGS AND OLIGONUCLEOTIDE SEQUENCES CONTAINING THEM | STERLING WINTHROP INC. (US) | 1994-10-13 | — | — | WO | disclosed |
| US-5256775-A | Having two or more phosphoramidiate linkages | GILEAD SCIENCES, INC. (US) | 1993-10-26 | — | — | US | disclosed |
| EP-0476071-A4 | EXONUCLEASE-RESISTANT OLIGONUCLEOTIDES AND METHODS FOR PREPARING THE SAME | — | 1992-11-04 | — | — | EP | disclosed |
| EP-0476071-A1 | EXONUCLEASE-RESISTANT OLIGONUCLEOTIDES AND METHODS FOR PREPARING THE SAME | GILEAD SCIENCES, INC. (US) | 1992-03-25 | — | — | EP | disclosed |
| WO-1990015065-A1 | EXONUCLEASE-RESISTANT OLIGONUCLEOTIDES AND METHODS FOR PREPARING THE SAME | GILEAD SCIENCES, INC. (US) | 1990-12-13 | — | — | WO | disclosed |