Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSPO | P30536 | 4/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4261408 | 0.88 | MAPT (0.36) | MAPTKDM4EALDH1A1POLB | |
| SCHEMBL4261398 | 0.85 | DNM1 (0.34) | MAPTTSPO | |
| SCHEMBL4262350 | 0.83 | TSPO (0.38) | MAPTKDM4EALDH1A1TSPO | |
| SCHEMBL4267403 | 0.82 | MAPT (0.39) | MAPTKDM4EALDH1A1TSPOPOLB | |
| SCHEMBL4260565 | 0.78 | MAPT (0.35) | MAPTALDH1A1POLB | |
| SCHEMBL4267819 | 0.76 | DNM1 (0.33) | MAPT | |
| SCHEMBL4254141 | 0.74 | MAPT (0.39) | MAPTKDM4EALDH1A1POLBPSEN1 | |
| SCHEMBL4261403 | 0.70 | MAPT (0.43) | MAPTKDM4EALDH1A1POLBPSEN1 | |
| SCHEMBL4267934 | 0.66 | MAPT (0.42) | MAPTKDM4EALDH1A1POLBPSEN1 | |
| SCHEMBL5999369 | 0.66 | MAPT (0.49) | MAPTKDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090242876-A1 | CARBAZOLE COMPOUNDS | KONINKLIJKE PHILIPS ELECTRONICS, N.V. (NL) | 2009-10-01 | — | — | US | disclosed |
| EP-1838671-B1 | 9,9'- AND 2,2'-SUBSTITUTED 3,3'-BICARBAZOLYL DERIVATIVES FOR USE IN SEMICONDUCTING MATERIALS AS A HOST MATRIX FOR PHOSPHORESCENT EMITTERS | KONINKL PHILIPS ELECTRONICS NV (NL) | 2008-06-04 | — | — | EP | disclosed |
| EP-1838671-A2 | 9,9'- AND 2,2'-SUBSTITUTED 3,3'-BICARBAZOLYL DERIVATIVES FOR USE IN SEMICONDUCTING MATERIALS AS A HOST MATRIX FOR PHOSPHORESCENT EMITTERS | Koninklijke Philips Electronics N.V. (NL) | 2007-10-03 | — | — | EP | disclosed |
| WO-2006061759-A2 | 9 , 9 ' - AND 2 , 2 ' -SUBSTITUTED 3 , 3 ' -BICARBAZOLYL DERIVATIVES FOR USE IN SEMICONDUCTING MATERIALS AS A HOST MATRIX FOR PHOSPHORESCENT EMITTERS | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 2006-06-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090242876-A1 | CARBAZOLE COMPOUNDS | CCNI, IL33, PAICS | MAPT 2051/4885KDM4E 3143/4885ALDH1A1 1152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.