Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 13/20 | 0.47 |
| ▸ | MMP1 | P03956 | 3/20 | 0.36 |
| ▸ | PTPRF | P10586 | 1/20 | 0.34 |
| ▸ | PTPRA | P18433 | 1/20 | 0.34 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5768014 | 0.86 | PTPN1 (0.40) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL4274375 | 0.80 | ADAMTS4 (0.36) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL4267605 | 0.77 | PTPN1 (0.47) | PTPN1MMP1PTPRFPTPRAPTPN7 | |
| SCHEMBL4800199 | 0.73 | PTPN1 (0.38) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL4264218 | 0.73 | MTNR1A (0.40) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL5187438 | 0.73 | PTPN1 (0.39) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL4806726 | 0.73 | PTPN1 (0.38) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL4263424 | 0.72 | PTPN1 (0.68) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL5742279 | 0.70 | MTNR1A (0.38) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL4261640 | 0.66 | PTPN1 (0.38) | PTPN1PTPRFPTPRAPTPN7DUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090082392-A1 | Substituted Carboxylic Acids | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY LLC | 2009-03-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090082392-A1 | Substituted Carboxylic Acids | PTPRJ, PTPRS, PTPRG | PTPN1 16/4885MMP1 2800/4885PTPRF 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.