Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 11/20 | 0.40 |
| ▸ | PTPRF | P10586 | 1/20 | 0.40 |
| ▸ | PTPRA | P18433 | 1/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 6/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 2/20 | 0.36 |
| ▸ | CPB1 | P15086 | 1/20 | 0.36 |
| ▸ | CPA3 | P15088 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4274375 | 0.92 | ADAMTS4 (0.36) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL4267609 | 0.86 | PTPN1 (0.47) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL4800199 | 0.82 | PTPN1 (0.38) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL4264218 | 0.80 | MTNR1A (0.40) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL4806726 | 0.79 | PTPN1 (0.38) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL5187438 | 0.78 | PTPN1 (0.39) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL4264656 | 0.77 | PPARA (0.35) | PTPN1DUSP3MMECPA1 | |
| SCHEMBL5742279 | 0.77 | MTNR1A (0.38) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL4262211 | 0.74 | PTPN1 (0.38) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL4261640 | 0.72 | PTPN1 (0.38) | PTPN1PTPRFPTPRAPTPN7DUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620420-A2 | SUBSTITUTED CARBOXYLIC ACIDS | The Institutes for Pharmaceutical Discovery, LLC (US) | 2006-02-01 | — | — | EP | disclosed |
| WO-2004099168-A2 | SUBSTITUTED CARBOXYLIC ACIDS | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, LLC (US) | 2004-11-18 | — | — | WO | disclosed |