SCHEMBL4267986

SCHEMBL4267986

CCC(CN)OS(=O)(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9325436 0.85 CA2 (0.33)
SCHEMBL778902 0.85 CA2 (0.33)
SCHEMBL28148821 0.84
Ammonia Solution, Strong SCHEMBL28101988 0.83 CA2 (0.32)
SCHEMBL25203219 0.79 ALDH1A1 (0.40)
SCHEMBL8329444 0.79
SCHEMBL17920061 0.79 MAPT (0.31)
SCHEMBL4127354 0.77 TSHR (0.30)
SCHEMBL6400269 0.77
SCHEMBL775892 0.77 PRKCA (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114669090-A Defoaming agent for phosphogypsum washing and preparation method thereof 湖北鑫钰鸿成科技有限公司 2022-06-28 CN claimed
CN-118577123-A Selective removal of NO from ship tail gasxAnd separating high purity CO2Method and system of (2) 浙江省白马湖实验室有限公司 2024-09-03 CN disclosed
CN-114669090-A Defoaming agent for phosphogypsum washing and preparation method thereof 湖北鑫钰鸿成科技有限公司 2022-06-28 CN disclosed
US-7608687-B2 Releasable linkage and compositions containing same ALZA CORPORATION (US) 2009-10-27 US disclosed
US-20080152702-A1 Releasable linkage and compositions containing same ZALIPSKY SAMUEL 2008-06-26 US disclosed
US-7390780-B2 Gene delivery mediated by liposome-DNA complex with cleavable peg surface modification ALZA CORPORATION (US) 2008-06-24 US disclosed
EP-1880736-A1 Releasable linkage and composition containing same Alza Corporation (US) 2008-01-23 EP disclosed
US-7285622-B2 Releasable linkage and compositions containing same ALZA CORPORATION (US) 2007-10-23 US disclosed
US-7112337-B2 Liposome composition for delivery of nucleic acid ALZA CORPORATION (US) 2006-09-26 US disclosed
US-7052673-B2 Pharmaceuticals for the imaging of angiogenic disorders BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) 2006-05-30 US disclosed
US-20030211079-A1 Releasable linkage and compositions containing same ALZA CORPORATION 2003-11-13 US disclosed
US-20030180305-A1 Pharmaceuticals for the imaging of angiogenic disorders LANTHEUS MEDICAL IMAGING, INC. 2003-09-25 US disclosed
US-6605299-B2 Hydrophilic polymer covalently and reversibly linked to amine-containing ligand through dithiobenzyl linkage; improves blood circulation time ALZA CORPORATION 2003-08-12 US disclosed
WO-2003053409-A1 LIPOSOME COMPOSITION FOR DELIVERY OF NUCLEIC ACID ALZA CORPORATION (US) 2003-07-03 WO disclosed
US-20030031704-A1 Liposome mixture of a lipid that is neutral in charge at physiologic pH and positively charged at pH values less than physiological pH, and a lipid joined to a hydrophilic polymer by an aromatic disulfide linkage, associated with a nucleic ALZA CORPORATION 2003-02-13 US disclosed
US-20020128195-A1 Releasable linkage and compositions containing same ALZA CORPORATION 2002-09-12 US disclosed
US-20020106325-A1 Simultaneous imaging of cardiac perfusion and a vitronectin receptor targeted imaging agent CARPENTER ALAN P (US) 2002-08-08 US disclosed
US-6342244-B1 HYDROPHILIC POLYMER COVALENTLY YET REVERSIBLY LINKED TO A AMINE-CONTAINING LIGAND THROUGH A DITHIOBENZYL LINKAGE; MODIFICATION OF VARIOUS SUBSTRATES, SUCH AS POLYPEPTIDES, DRUGS AND LIPOSOMES; UPON CLEAVAGE OF THE LINKAGE, THE LIGAND ALZA CORPORATION 2002-01-29 US disclosed
EP-1173221-A2 RELEASABLE LINKAGE AND COMPOSITIONS CONTAINING SAME Alza Corporation (US) 2002-01-23 EP disclosed
WO-2000064483-A2 RELEASABLE LINKAGE AND COMPOSITIONS CONTAINING SAME ALZA CORPORATION (US) 2000-11-02 WO disclosed