Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 2/20 | 0.65 |
| ▸ | CDK9 | P50750 | 2/20 | 0.65 |
| ▸ | HASPIN | Q8TF76 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | DYRK1A | Q13627 | 10/20 | 0.47 |
| ▸ | GSK3B | P49841 | 4/20 | 0.47 |
| ▸ | NFATC1 | O95644 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.42 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4268145 | 1.00 | CCNT1 (0.65) | CCNT1CDK9HASPINHPGDHTT | |
| SCHEMBL27773730 | 0.77 | DYRK1A (0.51) | CCNT1CDK9HASPINHPGDDYRK1A | |
| SCHEMBL2268299 | 0.77 | CCNT1 (0.62) | CCNT1CDK9HASPINDYRK1AGSK3B | |
| SCHEMBL29664462 | 0.77 | CCNT1 (0.62) | CCNT1CDK9HASPINDYRK1AGSK3B | |
| Hydrochloric Acid SCHEMBL3831446 | 0.76 | CCNT1 (0.60) | CCNT1CDK9HASPINDYRK1AGSK3B | |
| SCHEMBL31355128 | 0.75 | HTT (1.00) | HPGDHTTMAPTGAATDP1 | |
| SCHEMBL5167169 | 0.75 | HTT (1.00) | HPGDHTTMAPTGAATDP1 | |
| SCHEMBL2189141 | 0.75 | HTT (1.00) | HPGDHTTMAPTGAATDP1 | |
| SCHEMBL2189137 | 0.75 | HTT (1.00) | HPGDHTTMAPTGAATDP1 | |
| SCHEMBL6753342 | 0.73 | APP (0.63) | CCNT1CDK9HASPINDYRK1AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080064715-A1 | 6-Azaindole Compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-03-13 | — | — | US | claimed |
| US-7608627-B2 | I kappa B kinase inhibition; diabetes; (7-Chloro-1H-pyrrolo[2,3-c]pyridin-2-yl)methanol; N-Benzyl-7-chloro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-27 | — | — | US | disclosed |
| US-20080064715-A1 | 6-Azaindole Compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064715-A1 | 6-Azaindole Compound | RELA, NFKBIA, GPR119 | CCNT1 572/4885CDK9 73/4885HASPIN 1328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.