⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7436380 | 0.73 | — | — | |
| SCHEMBL2777592 | 0.69 | — | — | |
| SCHEMBL8699648 | 0.63 | — | — | |
| SCHEMBL7836944 | 0.60 | — | — | |
| SCHEMBL4254738 | 0.59 | — | — | |
| SCHEMBL2007098 | 0.59 | GSK3A (0.39) | — | |
| SCHEMBL447698 | 0.56 | — | — | |
| SCHEMBL3462882 | 0.55 | CRBN (0.39) | — | |
| SCHEMBL918294 | 0.54 | ADRA2A (0.31) | — | |
| SCHEMBL20077863 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023205680-A1 | PI3Kα INHIBITORS | SYNNOVATION THERAPEUTICS, INC. (US) | 2023-10-26 | — | — | WO | claimed |
| WO-2023165591-A1 | COMPOUNDS AND THEIR USES AS LPAR5 ANTAGONISTS | IMMUTHER PHARMATECH (SHANGHAI) CO., LTD. (CN) | 2023-09-07 | — | — | WO | claimed |
| EP-1989204-B1 | PYRAZOLOQUINOLONES ARE POTENT PARP INHIBITORS | ABBVIE INC (US) | 2014-05-21 | — | — | EP | claimed |
| EP-1252161-A1 | PYRROLO-ISOQUINOLINE AND TETRAHYDROPYRROLO-ISOQUINOLINE DERIVATIVES AND THEIR USE AS MEDIATORS OF THE 5-HT7 RECEPTOR | Wyeth (US) | 2002-10-30 | — | — | EP | claimed |
| WO-2001057039-A1 | PYRROLO-ISOQUINOLINE AND TETRAHYDROPYRROLO-ISOQUINOLINE DERIVATIVES AND THEIR USE AS MEDIATORS OF THE 5-HT7 RECEPTOR | WYETH (US) | 2001-08-09 | — | — | WO | claimed |
| CN-1218472-A | Pharmaceutically useful compounds | ASTRA PHARMA PROD (GB) | 1999-06-02 | — | — | CN | claimed |
| EP-4531849-A1 | HETEROCYCLIC PAD4 INHIBITORS | CELGENE CORPORATION (US) | 2025-04-09 | — | — | EP | disclosed |
| CN-119604287-A | Heterocyclic PAD4 inhibitors | 细胞基因公司 | 2025-03-11 | — | — | CN | disclosed |
| CN-117377671-A | Diacylglycerol kinase modulating compounds | 吉利德科学公司 | 2024-01-09 | — | — | CN | disclosed |
| WO-2023230609-A1 | HETEROCYCLIC PAD4 INHIBITORS | CELGENE CORPORATION (US) | 2023-11-30 | — | — | WO | disclosed |
| WO-2023205680-A1 | PI3Kα INHIBITORS | SYNNOVATION THERAPEUTICS, INC. (US) | 2023-10-26 | — | — | WO | disclosed |
| CN-115677701-A | Benzo heterocyclic compound and preparation method and application thereof | 昆药集团股份有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-115087486-A | Substituted bicyclic and tricyclic ureas and amides, analogs thereof, and methods of use thereof | 爱彼特生物制药公司 | 2022-09-20 | — | — | CN | disclosed |
| EP-0293777-B1 | CARDIOTONIC TRICYCLIC OXAZOLONES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-12-23 | — | — | EP | disclosed |
| EP-0292711-B1 | CARDIOTONIC TRICYCLIC IMIDAZOLONES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-03-11 | — | — | EP | disclosed |
| US-4803210-A | Cardiotonic tricyclic oxazolones | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-02-07 | — | — | US | disclosed |
| EP-0293777-A1 | Cardiotonic tricyclic oxazolones | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-12-07 | — | — | EP | disclosed |
| EP-0292711-A1 | Cardiotonic tricyclic imidazolones | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-11-30 | — | — | EP | disclosed |
| US-4743607-A | ENHANCING MYOCARDIAL CONTRACTILE FORCE | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-05-10 | — | — | US | disclosed |
| EP-0022078-B1 | PYRAZOLO-QUINOLINES, PROCESSES FOR THEIR PRODUCTION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CIBA-GEIGY AG (CH) | 1984-07-25 | — | — | EP | disclosed |