SCHEMBL2007098

SCHEMBL2007098

O=C1C=CC2=CCNC=C2C1

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GSK3A P49840 1/20 0.39
GSK3B P49841 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17100497 0.65
SCHEMBL277815 0.60
SCHEMBL8699648 0.60
SCHEMBL7711268 0.60 GSK3A (0.43) GSK3AGSK3B
SCHEMBL4268178 0.59
SCHEMBL2419065 0.56 GSK3A (0.39) GSK3AGSK3B
SCHEMBL3462882 0.56 CRBN (0.39)
SCHEMBL366153 0.56 GSK3A (0.71) GSK3AGSK3B
SCHEMBL918294 0.55 ADRA2A (0.31)
SCHEMBL337485 0.55 GSK3A (0.42) GSK3AGSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190194138-A1 7H- azulene [1,2,3-i,j] isoquinolin-7-one compound, single crystal and use thereof UNIV HUNAN CHINESE MEDICINE (CN) 2019-06-27 US claimed
EP-3212634-A1 COMPOUNDS AND METHODS TO SUPPRESS AUTOIMMUNE RESPONSE OREGON STATE UNIVERSITY (US) 2017-09-06 EP claimed
WO-2016069780-A1 COMPOUNDS AND METHODS TO SUPPRESS AUTOIMMUNE RESPONSE OREGON STATE UNIVERSITY (US) 2016-05-06 WO claimed
EP-2032141-A1 INHIBITORS OF JANUS KINASES Merck & Co., Inc. (US) 2009-03-11 EP claimed
WO-2007145957-A1 INHIBITORS OF JANUS KINASES MERCK & CO., INC. (US) 2007-12-21 WO claimed
WO-2005105814-A1 TETRACYCLIC INHIBITORS OF JANUS KINASES INCYTE CORPORATION (US) 2005-11-10 WO claimed
US-5925336-A Aqueous nail coating composition containing copolymerized colorants EASTMAN CHEMICAL COMPANY (US) 1999-07-20 US claimed
US-5744129-A Aqueous lip gloss and cosmetic compositions containing colored sulfopolyesters EASTMAN CHEMICAL COMPANY 1998-04-28 US claimed
US-5735907-A COLORANT REACTED INTO OR ONTO POLYMER BACKBONE CLAIROL, INC. (US) 1998-04-07 US claimed
EP-0605566-A1 LIGHT-ABSORBING POLYURETHANE COMPOSITIONS AND THERMOPLASTIC POLYMERS COLORED THEREWITH EASTMAN CHEMICAL COMPANY (US) 1994-07-13 EP claimed
WO-1993006147-A1 LIGHT-ABSORBING POLYURETHANE COMPOSITIONS AND THERMOPLASTIC POLYMERS COLORED THEREWITH EASTMAN KODAK COMPANY (US) 1993-04-01 WO claimed
US-5194463-A LIGHT-ABSORBING POLYURETHANE COMPOSITIONS AND THERMOPLASTIC POLYMERS COLORED THEREWITH EASTMAN KODAK COMPANY (US) 1993-03-16 US claimed
JP-52151320-A None JP disclosed
EP-4688959-A2 NAPHTHALIMIDE DYES AND USES IN NUCLEIC ACID SEQUENCING Illumina, Inc. (US) 2026-02-11 EP disclosed
WO-2024206407-A2 NAPHTHALIMIDE DYES AND USES IN NUCLEIC ACID SEQUENCING ILLUMINA, INC. (US) 2024-10-03 WO disclosed
US-20240327910-A1 NAPHTHALIMIDE DYES AND USES IN NUCLEIC ACID SEQUENCING ILLUMINA, INC. 2024-10-03 US disclosed
US-4618555-A PHOTOSENSITIVITY; DURABILITY MITSUBISHI CHEMICAL IND., LTD. (JP) 1986-10-21 US disclosed
EP-0150707-A1 Electrophotographic photoreceptor MITSUBISHI KASEI CORPORATION (JP) 1985-08-07 EP disclosed
EP-0106430-A2 Isoquinoline derivatives as immuno-regulators ELI LILLY AND COMPANY (US) 1984-04-25 EP disclosed
JP-S52151320-A 3,4-DICHLORO-7H-BENZO(DE)-PYRAZOLO(5,1-A)ISOQUINOLINE-7-ONE DERIVATIVE MITSUBISHI CHEM IND LTD 1977-12-15 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190194138-A1 7H- azulene [1,2,3-i,j] isoquinolin-7-one compound, single crystal and use thereof CALU, CACNA1S, BACE1 GSK3A 3818/4885GSK3B 3928/4885
US-20240327910-A1 NAPHTHALIMIDE DYES AND USES IN NUCLEIC ACID SEQUENCING NDC1, DNTT, POLRMT GSK3A 4839/4885GSK3B 4823/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.