Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KLK7 | P49862 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4267439 | 0.81 | ALDH1A1 (0.59) | KMT2AALDH1A1CYP2C9MEN1CYP1A2 | |
| SCHEMBL221092 | 0.80 | ALDH1A1 (0.72) | KMT2AALDH1A1CYP2C9MEN1CYP1A2 | |
| SCHEMBL11385742 | 0.78 | ALDH1A1 (0.56) | KMT2AALDH1A1CYP2C9MEN1CYP1A2 | |
| SCHEMBL11388585 | 0.77 | ALDH1A1 (0.55) | KMT2AALDH1A1CYP2C9MEN1CYP1A2 | |
| SCHEMBL13479820 | 0.76 | KMT2A (0.53) | KMT2AALDH1A1CYP2C9MEN1CYP1A2 | |
| SCHEMBL6693868 | 0.76 | KMT2A (1.00) | KMT2AALDH1A1CYP2C9MEN1HPGD | |
| SCHEMBL28658136 | 0.76 | ALDH1A1 (1.00) | KMT2AALDH1A1CYP2C9MEN1CYP1A2 | |
| SCHEMBL1562501 | 0.76 | ALDH1A1 (0.61) | KMT2AALDH1A1CYP2C9MEN1CYP1A2 | |
| SCHEMBL8610167 | 0.75 | ALDH1A1 (0.65) | KMT2AALDH1A1CYP2C9MEN1CYP1A2 | |
| SCHEMBL4279628 | 0.75 | ALDH1A1 (0.65) | KMT2AALDH1A1CYP2C9MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5246969-A | — | — | None | — | — | JP | disclosed |
| US-7608627-B2 | I kappa B kinase inhibition; diabetes; (7-Chloro-1H-pyrrolo[2,3-c]pyridin-2-yl)methanol; N-Benzyl-7-chloro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-27 | — | — | US | disclosed |
| US-20080064715-A1 | 6-Azaindole Compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-03-13 | — | — | US | disclosed |
| JP-H05246969-A | AMINOXYFATTY ACID DERIVATIVE AND ENZYME INHIBITOR | SANKYO CO LTD | 1993-09-24 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064715-A1 | 6-Azaindole Compound | RELA, NFKBIA, GPR119 | KMT2A 1114/4885ALDH1A1 3508/4885CYP2C9 1914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.